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CD166/ALCAM Protein, Cynomolgus, Recombinant (His)

(Synonyms: activated leukocyte cell adhesion molecule) Copy Product Info

Synonyms: activated leukocyte cell adhesion molecule

Catalog No. TMPY-03520 Copy Product Info
CD166/ALCAM Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.10 kDa and the accession number is G7NZQ8.
Pack SizePriceEUR StockGlobal StockQuantity
5 µg71 €7-10 days7-10 days
10 µg116 €7-10 days7-10 days
20 µg187 €7-10 days7-10 days
50 µg377 €7-10 days7-10 days
100 µg730 €7-10 days7-10 days
For In stock only · Estimated delivery: EUR Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Information

Bioactivity
Bioactivity
Immobilized Cynomolgus ALCAM, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-ALCAM Antibody, hFc Tag with the EC50 of 0.62 μg/ml determined by ELISA.
Description
CD166/ALCAM Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.10 kDa and the accession number is G7NZQ8.
Species
Cynomolgus
Expression System
HEK293 Cells
TagC-His
Accession NumberG7NZQ8
ConstructionTrp28-Lys527
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonymsactivated leukocyte cell adhesion molecule
Research Background
Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression promote BM formation in NSCLC through increased tumor cell dissemination and interaction with the brain endothelial cells. Therefore, ALCAM could be targeted to reduce the occurrence of BM.
Chemical Properties
Molecular Weight57.10 kDa (Predicted); 70-85 kDa (Due to glycosylation)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: CD166/ALCAM Protein, Cynomolgus, Recombinant (His) chemical structure | CD166/ALCAM Protein, Cynomolgus, Recombinant (His) molecular weight