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Anti-SLAMF6 Antibody-APC (2C420)

🥰Excellent
Catalog No. TMAY-02161A

Anti-SLAMF6 Antibody-APC (2C420) is a APC-conjugated Rabbit antibody targeting SLAMF6. Anti-SLAMF6 Antibody-APC (2C420) can be used in FCM.

Anti-SLAMF6 Antibody-APC (2C420)

Anti-SLAMF6 Antibody-APC (2C420)

🥰Excellent
Catalog No. TMAY-02161A
Anti-SLAMF6 Antibody-APC (2C420) is a APC-conjugated Rabbit antibody targeting SLAMF6. Anti-SLAMF6 Antibody-APC (2C420) can be used in FCM.
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Product Introduction

Bioactivity
Description
Anti-SLAMF6 Antibody-APC (2C420) is a APC-conjugated Rabbit antibody targeting SLAMF6. Anti-SLAMF6 Antibody-APC (2C420) can be used in FCM.
Ig Type
Monoclonal Rabbit IgG
Clone
2C420
Reactivity
Human
Verified Activity
Flow cytometric analysis of Human SLAMF6(CD352) expression on human whole blood lymphocytes. Cells were stained with APC-conjugated anti-Human SLAMF6(CD352). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.
Application
FCM
Recommended Dose
5 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human Ly108/SLAMF6 (rh Ly108/SLAMF6; TMPY-01914; Q96DU3-1; Met1-Met226) and conjugated with APC under optimum conditions, the unreacted APC was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.09% sodium azide
Research BackgroundSLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly18 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly18 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6 / Ly18 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6 / Ly18 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6 / Ly18 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients.
Related Conjugates and Formulations
Conjucates
APC
Others Formats
Unconjugated/FITC/PE
Antibody Types Available
4
Antigen Details
Immunogen
Recombinant Human Ly108/SLAMF6 Protein (TMPY-01914)
Antigen Species
Human
Biology Area
ITIM/ITAM Immunoreceptors and Related Molecules
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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