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Anti-JUN Antibody (7A403) (Synonyms: V-jun avian sarcoma virus 17 oncogene homolog, Transcription factor Jun, ...)

Catalog No. TMAC-00860 Copy Product Info
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Anti-JUN Antibody (7A403) is a Rabbit antibody targeting JUN. Anti-JUN Antibody (7A403) can be used in ICC,IHC,IP,WB.

Anti-JUN Antibody (7A403)

Copy Product Info
🥰Excellent
Catalog No. TMAC-00860
Synonyms V-jun avian sarcoma virus 17 oncogene homolog, Transcription factor Jun, Transcription factor AP-1 subunit Jun, Proto-oncogene c-Jun, p39, JUN, Activator protein 1 (AP1)

Anti-JUN Antibody (7A403) is a Rabbit antibody targeting JUN. Anti-JUN Antibody (7A403) can be used in ICC,IHC,IP,WB.

Anti-JUN Antibody
(7A403)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2987-10 days7-10 days
100 μL$4967-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-JUN Antibody (7A403) is a Rabbit antibody targeting JUN. Anti-JUN Antibody (7A403) can be used in ICC,IHC,IP,WB.
SynonymsV-jun avian sarcoma virus 17 oncogene homolog, Transcription factor Jun, Transcription factor AP-1 subunit Jun, Proto-oncogene c-Jun, p39, JUN, Activator protein 1 (AP1)
Ig Type
IgG
Clone
7A403
Reactivity
Human,Mouse,Rat
Verified Activity
1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-c-Jun antibody. Counter stained with hematoxylin.
2. ICC staining c-Jun in L6 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining c-Jun in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. ICC staining c-Jun in NIH/3T3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
verifiedActivityverifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:1000; IHC: 1:50-200; ICC: 1:100-500
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundGenes belonging to the Jun and Fos oncogene families encode nuclear proteins that are associated with a number of transcriptional complexes. The c-Jun protein is a major component of the transcription factor AP-1, originally shown to mediate phorbol ester tumor promoter (TPA)-induced expression of responsive genes through the TPA-response element (TRE). The Jun proteins form homo- and heterodimers which bind the TRE, while Fos proteins are active only as heterodimers with any of the Jun proteins. Fos/Jun heterodimers have a much higher affinity for the TRE than Jun homodimers. Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain. An inhibitor of Fos/Jun function, termed IP-1, associates with Fos and Jun and is inactivated upon phosphorylation induced by the cAMP-dependent protein kinase A (PKA).
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 43 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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