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Anti-Syndecan-4 Antibody-PE (7T56)
🥰Excellent
Catalog No. TMAY-03438P
Anti-Syndecan-4 Antibody-PE (7T56) is a PE-conjugated Rabbit antibody targeting Syndecan-4. Anti-Syndecan-4 Antibody-PE (7T56) can be used in FCM.
Anti-Syndecan-4 Antibody-PE (7T56)
Anti-Syndecan-4 Antibody-PE (7T56)
🥰Excellent
Catalog No. TMAY-03438P
Anti-Syndecan-4 Antibody-PE (7T56) is a PE-conjugated Rabbit antibody targeting Syndecan-4. Anti-Syndecan-4 Antibody-PE (7T56) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Syndecan-4 Antibody-PE (7T56) is a PE-conjugated Rabbit antibody targeting Syndecan-4. Anti-Syndecan-4 Antibody-PE (7T56) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 7T56 |
| Reactivity | Mouse |
| Verified Activity | Flow cytometric analysis of mouse SDC4 expression on mouse splenocytes. BABL/c splenocytes were stained with PE-conjugated anti-Mouse SDC4 and FITC-conjugated anti-Mouse CD3 (BD Pharmingen™ Cat. No.553061, left) or APC-conjugated anti-Mouse CD19 (BD Pharmingen™ Cat. No.550992, right). |
| Application | FCM |
| Recommended Dose | 2 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Syndecan-4 / SDC4 (rM Syndecan-4 / SDC4; TMPY-02392; O35988; Met1-Val146) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | SDC4 (Syndecan-4), also known as Syn4, is a transmembrane heparan sulfate proteoglycan that co-operates with integrins during cell-matrix interactions for the assembly of focal adhesions and actin stress fibers and in the phosphorylation of focal adhesion kinase (FAK) on Tyr397. Syndecan-4 plays roles in the formation of focal adhesions and stress fibers. The cytoplasmic domain of syndecan-4 interacts with several signalling and structural proteins, and both extracellular and cytoplasmic domains are necessary for regulated activation of associated transmembrane receptors. Syndecan-4/SDC4 is a heparan sulfate proteoglycan and works as a coreceptor for various growth factors. SDC4 deficiency limits neointimal formation after vascular injury by regulating vascular smooth muscle cells (VSMCs) proliferation and vascular progenitor cells (VPCs) mobilization. Therefore, SDC4 may be a novel therapeutic target for preventing arterial restenosis after angioplasty. |
| Conjucates | PE |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Mouse Syndecan-4 / SDC4 protein (TMPY-02392) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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