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Anti-MMP17 Antibody (1E489) is a Rabbit antibody targeting MMP17. Anti-MMP17 Antibody (1E489) can be used in ICC,IF,IHC,WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $298 | 7-10 days | |
100 μL | $497 | 7-10 days |
Description | Anti-MMP17 Antibody (1E489) is a Rabbit antibody targeting MMP17. Anti-MMP17 Antibody (1E489) can be used in ICC,IF,IHC,WB. |
Synonyms | MTMMP4, MT-MMP 4, MTMMP 4, MT4-MMP, MT4MMP, MT4 MMP, MT MMP4, MT MMP 4, MMP17_HUMAN, MMP 17, Membrane-type-4 matrix metalloproteinase, Membrane-type matrix metalloproteinase 4, Membrane type matrix metalloproteinase 4, Membrane type 4 matrix metalloproteinase, Matrix metalloproteinase-17, Matrix metalloproteinase 17 membrane inserted, Matrix metalloproteinase 17 |
Ig Type | IgG |
Reactivity | Human,Mouse,Rat |
Verified Activity | 1. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-MMP17 antibody. Counter stained with hematoxylin. 2. ICC staining MMP17 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining MMP17 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
Application | |
Recommended Dose | IHC: 1:50; ICC: 1:50 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | Recombinant Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Cleaves pro-TNF-alpha at the '74-Ala-|-Gln-75' site. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein: human MMP17 aa 1-250 |
Antigen Species | human |
Uniprot ID |
Molecular Weight | Theoretical: 67 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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