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Anti-Chymotrypsin C Antibody (2P796)
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Catalog No. TMAY-01866
Alias ELA4, CLCR, chymotrypsin C (caldecrin)
Anti-Chymotrypsin C Antibody (2P796) is a Rabbit antibody targeting Chymotrypsin C. Anti-Chymotrypsin C Antibody (2P796) can be used in ELISA.
Anti-Chymotrypsin C Antibody (2P796)
Anti-Chymotrypsin C Antibody (2P796)
😃Good
Catalog No. TMAY-01866Alias ELA4, CLCR, chymotrypsin C (caldecrin)
Anti-Chymotrypsin C Antibody (2P796) is a Rabbit antibody targeting Chymotrypsin C. Anti-Chymotrypsin C Antibody (2P796) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $268 | 7-10 days |
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Product Introduction
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Antigen Details
Chemical Properties
| Description | Anti-Chymotrypsin C Antibody (2P796) is a Rabbit antibody targeting Chymotrypsin C. Anti-Chymotrypsin C Antibody (2P796) can be used in ELISA. |
| Alias | ELA4, CLCR, chymotrypsin C (caldecrin) |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 2P796 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CTRC / chymotrypsin C (rh CTRC / chymotrypsin C; TMPY-02480; Q99895; Met1-Leu268). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Chymotrypsin C (abbreviated for CTRC), also known as caldecrin or elastase4, is a digestive enzyme of the peptidase S1 family. This enzyme is synthesized as an inactivate chymotrypsinogen. On cleavage by trypsin into two parts that activate each other by removing two small peptides in a trans-proteolysis, chymotrypsin C produced. N-linked glycosylation of human CTRC is required for efficient folding and secretion, however, the N-linked glycan is unimportant for enzyme activity or inhibitor binding. It has been proposed that CTRC is a key regulator of digestive zymogen activation and a physiological co-activator of digestive carboxypeptidases proCPA1 and proCPA2. Mutations that abolish activity or secretion of CTRC increase the risk for chronic pancreatitis. It's speculated that CTRC might regulate pancreatic cancer cell migration in relation to cytokeratin 18 expression. The pancreatic cancer cell migration ability was downregulated in pancreatic cancer Aspc-1 cells that overexpressed CTRC, whereas the cell migration ability was upregulated in Aspc-1 cells in which CTRC was suppressed. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human CTRC / chymotrypsin C protein (TMPY-02480) |
| Antigen Species | Human |
| Biology Area | Serine Proteases and Regulators |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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