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CyPep-1

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Catalog No. TP3011Cas No. 1319804-91-5

CyPep-1 is a novel cationic lytic peptide with antitumor activity. It exerts potent cytotoxicity by interacting with the negatively charged membranes of cancer cells. CyPep-1 demonstrates strong cell lytic activity against cancer cells both in vitro and in vivo, making it useful for researching solid tumors.

CyPep-1

CyPep-1

😃Good
Catalog No. TP3011Cas No. 1319804-91-5
CyPep-1 is a novel cationic lytic peptide with antitumor activity. It exerts potent cytotoxicity by interacting with the negatively charged membranes of cancer cells. CyPep-1 demonstrates strong cell lytic activity against cancer cells both in vitro and in vivo, making it useful for researching solid tumors.
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
CyPep-1 is a novel cationic lytic peptide with antitumor activity. It exerts potent cytotoxicity by interacting with the negatively charged membranes of cancer cells. CyPep-1 demonstrates strong cell lytic activity against cancer cells both in vitro and in vivo, making it useful for researching solid tumors.
In vitro
CyPep-1 (0-40 μg/mL; 15-360 minutes) exhibits dose- and time-dependent cytotoxic effects on tumor cell lines, while affecting normal cell lines to a lesser extent.
In vivo
CyPep-1 (intratumoral injection; 1200 µg; single dose) demonstrates antitumor effects in a mouse model of breast cancer.
Chemical Properties
Molecular Weight3451.09
FormulaC152H265N57O35
Cas No.1319804-91-5
Smiles[C@@H](CC1=CC=C(O)C=C1)(NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CC3=CC=C(O)C=C3)N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)CCCCN)=O)[C@@H](C)O)=O)CC(C)C)=O)CCCNC(=N)N)=O)[C@@H](C)C)=O)C)=O)CCCCN)=O)C)=O)[C@H](CC)C)=O)=O)CCCCN)=O)CCCNC(=N)N)=O)C(N[C@H](C(N[C@@H](CCC(O)=O)C(O)=O)=O)[C@H](CC)C)=O
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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