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Anti-CCL3 Polyclonal Antibody
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Catalog No. TMAB-00310
Alias Tonsillar lymphocyte LD78 alpha protein, Small-inducible cytokine A3, SIS-beta, SCYA3, PAT 464.1, MIP1A, Macrophage inflammatory protein 1-alpha (MIP-1-alpha), G0S19-1, G0/G1 switch regulatory protein 19-1, CCL3, C-C motif chemokine 3
Anti-CCL3 Polyclonal Antibody is a Rabbit antibody targeting CCL3. Anti-CCL3 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
Anti-CCL3 Polyclonal Antibody
Anti-CCL3 Polyclonal Antibody
😃Good
Catalog No. TMAB-00310Alias Tonsillar lymphocyte LD78 alpha protein, Small-inducible cytokine A3, SIS-beta, SCYA3, PAT 464.1, MIP1A, Macrophage inflammatory protein 1-alpha (MIP-1-alpha), G0S19-1, G0/G1 switch regulatory protein 19-1, CCL3, C-C motif chemokine 3
Anti-CCL3 Polyclonal Antibody is a Rabbit antibody targeting CCL3. Anti-CCL3 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-CCL3 Polyclonal Antibody is a Rabbit antibody targeting CCL3. Anti-CCL3 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P. |
| Synonyms | Tonsillar lymphocyte LD78 alpha protein, Small-inducible cytokine A3, SIS-beta, SCYA3, PAT 464.1, MIP1A, Macrophage inflammatory protein 1-alpha (MIP-1-alpha), G0S19-1, G0/G1 switch regulatory protein 19-1, CCL3, C-C motif chemokine 3 |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse) |
| Verified Activity | Tissue/cell: rat exfoliated cells; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-MIP-1 Alpha/CCL3 Polyclonal Antibody, Unconjugated (TMAB-00310) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. |
| Tissue Specificity | Expressed in lung, spleen, and pancreas. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Macrophage Inflammatory Protein 1 alpha (MIP1 alpha) and MIP1 beta, two closely related but distinct proteins, were originally co-purified from medium conditioned by a LPS-stimulated murine macrophage cell line. Mature mouse MIP1 alpha shares approximately 77% and 70% amino acid identity with human MIP1 alpha and mouse MIP1 beta, respectively. MIP1 proteins are expressed primarily in T cells, B cells, and monocytes after antigen or mitogen stimulation. Has adhesive effects on lymphocytes. MIP1 alpha can inhibit the proliferation of hematopoietic stem cells in vitro as well as in vivo. A signal transducing receptor, designated the C-C chemokine receptor-1 (C-C CKR-1) with seven transmembrane domains that bind MIP1 alpha, MIP1 beta, MCP1 and RANTES with varying affinities, has been isolated. |
| Immunogen | KLH conjugated synthetic peptide: human MIP-1 alpha |
| Antigen Species | Human |
| Gene Name | Ccl3 |
| Gene ID | |
| Protein Name | C-C motif chemokine 3 |
| Uniprot ID | |
| Biology Area | HIV-related,Beta Chemokines (CC),Macrophage / Inflamm.,Blood cell antigens ELISA kits |
| Function | Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). |
| Molecular Weight | Theoretical: 8 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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