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MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH

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Catalog No. T39064Cas No. 1599440-25-1

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a degradable ADC linker used for synthesizing ADCs (antibody-drug conjugates).

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH

😃Good
Purity: 99.73%
Catalog No. T39064Cas No. 1599440-25-1
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a degradable ADC linker used for synthesizing ADCs (antibody-drug conjugates).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mg$30-In Stock
25 mg$48-In Stock
50 mg$68-In Stock
100 mg$89-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.73%
ee:100%
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COA LCMS HNMR CSFC

Product Introduction

Bioactivity
Description
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a degradable ADC linker used for synthesizing ADCs (antibody-drug conjugates).
Chemical Properties
Molecular Weight616.63
FormulaC28H36N6O10
Cas No.1599440-25-1
Smiles[C@H](CC1=CC=CC=C1)(C(NCC(NCOCC(O)=O)=O)=O)NC(CNC(CNC(CCCCCN2C(=O)C=CC2=O)=O)=O)=O
Relative Density.1.341 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80.00 mg/mL (129.74 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.6217 mL8.1086 mL16.2172 mL81.0859 mL
5 mM0.3243 mL1.6217 mL3.2434 mL16.2172 mL
10 mM0.1622 mL0.8109 mL1.6217 mL8.1086 mL
20 mM0.0811 mL0.4054 mL0.8109 mL4.0543 mL
50 mM0.0324 mL0.1622 mL0.3243 mL1.6217 mL
100 mM0.0162 mL0.0811 mL0.1622 mL0.8109 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
The above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOHMC-Gly-Gly-Phe-Gly-NH-CH-2-O-CH2COOHMCGlyGlyPheGlyNHCH2OCH2COOHMC Gly Gly Phe Gly NH CH2 O CH2COOHADCLinkerADC Linker
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