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Anti-Phospho-HER4/ERBB4 (Tyr1284) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HER4/ERBB4 (Tyr1284). Anti-Phospho-HER4/ERBB4 (Tyr1284) Polyclonal Antibody can be used in WB,IHC,IF.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $216 | 7-10 days | |
100 μL | $318 | 7-10 days |
Description | Anti-Phospho-HER4/ERBB4 (Tyr1284) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HER4/ERBB4 (Tyr1284). Anti-Phospho-HER4/ERBB4 (Tyr1284) Polyclonal Antibody can be used in WB,IHC,IF. |
Synonyms | p-HER4/ERBB4 (Y1284), p-HER4/ERBB4 (Tyr1284), HER4/ERBB4 (p-Y1284), HER4/ERBB4 (p-Tyr1284) |
Ig Type | IgG |
Reactivity | Human,Mouse,Rat |
Verified Activity | 1. Western blot analysis of lysates from HUVEC cells treated with EGF 200ng/ml 30'. The lane on the right is blocked with the phospho peptide. 2. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma. The picture on the right is blocked with the phospho peptide. 3. Immunofluorescence analysis of HeLa cells treated with EGF 200nM 5'. The picture on the right is blocked with the phospho peptide. |
Application | |
Recommended Dose | WB: 1:500-2000; IHC: 1:100-300; IF: 1:200-1000; |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Construction | Polyclonal Antibody |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Appearance | Liquid |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Research Background | This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008], |
Conjucates | Unconjugated |
Others Formats | Phospho |
Immunogen | A synthesized phosphopeptide: human HER4 around the phosphorylation site of Tyr1284 |
Antigen Species | human |
Uniprot ID |
Molecular Weight | Actual: 180 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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