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Anti-ANGPT2/Angiopoietin-2 Antibody (5L463) is a Mouse antibody targeting ANGPT2/Angiopoietin-2. Anti-ANGPT2/Angiopoietin-2 Antibody (5L463) can be used in WB,IP,IF,IHC.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $298 | 7-10 days | |
100 μL | $426 | 7-10 days |
Description | Anti-ANGPT2/Angiopoietin-2 Antibody (5L463) is a Mouse antibody targeting ANGPT2/Angiopoietin-2. Anti-ANGPT2/Angiopoietin-2 Antibody (5L463) can be used in WB,IP,IF,IHC. |
Synonyms | Tie2-ligand, ANGPT2, angiopoitin 2, angiopoietin-2B, angiopoietin-2a, Angiopoietin-2, angiopoietin 2, ANG-2, ANG2, AGPT2 |
Reactivity | Human,Mouse,Rat |
Verified Activity | 1. Western Blot analysis of Ang-2 expression in HUV-EC-C (A) and TF-1 (B) whole cell lysates. 2. Immunoperoxidase staining of formalin fixed, paraffin-embedded human placenta tissue showing cytoplasmic staining of trophoblastic cells at low (A) and high (B) magnification. |
Application | |
Recommended Dose | WB: 1:100-1000; IHC: 1:50-500; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | Hybridoma Monoclonal Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | Tie-1 and Tie-2 (also designated Tek) are novel cell surface receptor tyrosine kinases. The extracellular domain of Tie-1 has an unusual multidomain structure consisting of a cluster of three epidermal growth factor homology motifs localized between two immunoglobulin-like loops, which are followed by three Fibronectin type III repeats next to the transmembrane region. Angiopoietin-1 (Ang-1) is a secreted ligand for Tie-2. Preliminary biochemical analyses of Ang-1 reveal a potential Fibrinogen-like domain at the carboxy-terminus and coiled-coil regions in the amino-terminus. Ang-1 is an angiogenic factor that is thought to be involved in endothelial development. A related protein, angiopoietin-2 (Ang-2), has been identified as a naturally occurring antagonist of Ang-1 activation of Tie-2. In adult tissue, Ang-2 expression seems to be restricted to sites of vascular remodeling. |
Conjucates | Unconjugated |
Immunogen | Peptide |
Uniprot ID |
Molecular Weight | Theoretical: 62-70 kDa. |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. |
Transport | Shipping with blue ice. |
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