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Anti-ANGPT2/Angiopoietin-2 Antibody (5L463)

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Catalog No. TMAC-00205
Alias Tie2-ligand, ANGPT2, angiopoitin 2, angiopoietin-2B, angiopoietin-2a, Angiopoietin-2, angiopoietin 2, ANG-2, ANG2, AGPT2

Anti-ANGPT2/Angiopoietin-2 Antibody (5L463) is a Mouse antibody targeting ANGPT2/Angiopoietin-2. Anti-ANGPT2/Angiopoietin-2 Antibody (5L463) can be used in WB,IP,IF,IHC.

Anti-ANGPT2/Angiopoietin-2 Antibody (5L463)

Anti-ANGPT2/Angiopoietin-2 Antibody (5L463)

😃Good
Catalog No. TMAC-00205Alias Tie2-ligand, ANGPT2, angiopoitin 2, angiopoietin-2B, angiopoietin-2a, Angiopoietin-2, angiopoietin 2, ANG-2, ANG2, AGPT2
Anti-ANGPT2/Angiopoietin-2 Antibody (5L463) is a Mouse antibody targeting ANGPT2/Angiopoietin-2. Anti-ANGPT2/Angiopoietin-2 Antibody (5L463) can be used in WB,IP,IF,IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4267-10 days
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Product Introduction

Bioactivity
Description
Anti-ANGPT2/Angiopoietin-2 Antibody (5L463) is a Mouse antibody targeting ANGPT2/Angiopoietin-2. Anti-ANGPT2/Angiopoietin-2 Antibody (5L463) can be used in WB,IP,IF,IHC.
SynonymsTie2-ligand, ANGPT2, angiopoitin 2, angiopoietin-2B, angiopoietin-2a, Angiopoietin-2, angiopoietin 2, ANG-2, ANG2, AGPT2
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western Blot analysis of Ang-2 expression in HUV-EC-C (A) and TF-1 (B) whole cell lysates.
2. Immunoperoxidase staining of formalin fixed, paraffin-embedded human placenta tissue showing cytoplasmic staining of trophoblastic cells at low (A) and high (B) magnification.
Application
Recommended Dose
WB: 1:100-1000; IHC: 1:50-500; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundTie-1 and Tie-2 (also designated Tek) are novel cell surface receptor tyrosine kinases. The extracellular domain of Tie-1 has an unusual multidomain structure consisting of a cluster of three epidermal growth factor homology motifs localized between two immunoglobulin-like loops, which are followed by three Fibronectin type III repeats next to the transmembrane region. Angiopoietin-1 (Ang-1) is a secreted ligand for Tie-2. Preliminary biochemical analyses of Ang-1 reveal a potential Fibrinogen-like domain at the carboxy-terminus and coiled-coil regions in the amino-terminus. Ang-1 is an angiogenic factor that is thought to be involved in endothelial development. A related protein, angiopoietin-2 (Ang-2), has been identified as a naturally occurring antagonist of Ang-1 activation of Tie-2. In adult tissue, Ang-2 expression seems to be restricted to sites of vascular remodeling.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Peptide
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 62-70 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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