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Anti-Endothelin B Receptor Antibody (9N820)
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Catalog No. TMAC-01292
Anti-Endothelin B Receptor Antibody (9N820) is a Rabbit antibody targeting Endothelin B Receptor. Anti-Endothelin B Receptor Antibody (9N820) can be used in WB,IP.
Anti-Endothelin B Receptor Antibody (9N820)
Anti-Endothelin B Receptor Antibody (9N820)
😃Good
Catalog No. TMAC-01292
Anti-Endothelin B Receptor Antibody (9N820) is a Rabbit antibody targeting Endothelin B Receptor. Anti-Endothelin B Receptor Antibody (9N820) can be used in WB,IP.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $498 | 7-10 days |
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| Description | Anti-Endothelin B Receptor Antibody (9N820) is a Rabbit antibody targeting Endothelin B Receptor. Anti-Endothelin B Receptor Antibody (9N820) can be used in WB,IP. |
| Ig Type | IgG |
| Reactivity | Human,zebrafish |
| Application | |
| Recommended Dose | WB: 1:500-2000; IP: 1:10-50 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Endothelin receptor B (ETBR), also known as EDNRB, ETB, ETRB, HSCR and HSCR2, is a member of the guanine-binding, regulatory protein-coupled receptor family. Three isoforms of ETBR exist called isoform 1, isoform 2 and δ 3. ETBR is involved in the regulation of sodium excretion and glomular filtration rate (GFR). ETBR plays a role in the normal development of the neural crestderived cell lineages, epidermal melanocytes and enteric neurons. ETBR is expressed in lung, kidney, placenta, skeletal muscle and stem villi vessels. Both of the ET receptors, ETAR and ETBR, are activated by ET1, which results in inhibition of active lens sodium-potassium transport. Activation of the ET receptors also causes an increase in cytoplasmic calcium concentration in cultured lens epithelial cells. ETBR deficiency causes early onset dysfunction of the kidney, characterized by reduced sodium excretion, decreased GFR and slightly elevated blood pressure. Mutations in the gene encoding ETBR produce congenital aganglionic megacolon and pigment abnormalities. The multigenic disorder, Hirschsprung??s disease type 2, is also due to a mutation in the ETBR gene. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Antigen Species | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 50 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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