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Anti-HAS1 Polyclonal Antibody

😃Good
Catalog No. TMAB-00829

Anti-HAS1 Polyclonal Antibody is a Rabbit antibody targeting HAS1. Anti-HAS1 Polyclonal Antibody can be used in WB.

Anti-HAS1 Polyclonal Antibody

Anti-HAS1 Polyclonal Antibody

😃Good
Catalog No. TMAB-00829
Anti-HAS1 Polyclonal Antibody is a Rabbit antibody targeting HAS1. Anti-HAS1 Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$221 7-10 days
100 μL$372 7-10 days
200 μL$527 7-10 days
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Product Introduction

Bioactivity
Description
Anti-HAS1 Polyclonal Antibody is a Rabbit antibody targeting HAS1. Anti-HAS1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Pig,Cow,Sheep)
Verified Activity
Sample:
Lane 1: Mouse Testis Lysates
Lane 2: Mouse Spleen Lysates
Lane 3: Rat Testis Lysates
Lane 4: Rat Spleen Lysates
Lane 5: Human U-87 MG cell Lysates
Lane 6: Human DU145 cell Lysates
Primary: Anti-HAS1 (TMAB-00829) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 65 kDa
Observed band size: 65 kDa
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Multi-pass membrane protein
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundHAS1, HAS2 and HAS3 are HA Synthase proteins that synthesize HA (Hyaluronan or hyaluronic acid). The extracellular matrix in most vertebrates express HA, which is a high molecular weight linear polysaccharide composed of alternating glucuronic acid and N-acetylglucosamine residues linked by beta-1,3 and beta-1,4 glycosidic bonds. The three HAS genes show distinct patterns of expression during development and their protein products play significantly different roles in the formation of the HA matrix. Both HAS1 and HAS2 synthesize high molecular weight HA, whereas HAS3 produces lower molecular weight HA. The expression of the three HAS isoforms is more prominent in growing cells than in resting cells and is differentially regulated by various stimuli, suggesting distinct functional roles of the three proteins. HAS1 mRNA shows predominant expression in bone marrow mesenchymal progenitor cells and synovial cells.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Hyaluronan synthase 1
Antigen Species
Human
Gene ID
Uniprot ID
Biology Area
Extracellular Matrix,Stem cells,Axis formation and symmetry,ECM Proteins,Neurogenesis,Other Enzymes
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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