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Anti-HAS1 Polyclonal Antibody is a Rabbit antibody targeting HAS1. Anti-HAS1 Polyclonal Antibody can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $221 | 7-10 days | |
100 μL | $372 | 7-10 days | |
200 μL | $527 | 7-10 days |
Description | Anti-HAS1 Polyclonal Antibody is a Rabbit antibody targeting HAS1. Anti-HAS1 Polyclonal Antibody can be used in WB. |
Ig Type | IgG |
Reactivity | Human,Mouse,Rat (predicted:Pig,Cow,Sheep) |
Verified Activity | Sample: Lane 1: Mouse Testis Lysates Lane 2: Mouse Spleen Lysates Lane 3: Rat Testis Lysates Lane 4: Rat Spleen Lysates Lane 5: Human U-87 MG cell Lysates Lane 6: Human DU145 cell Lysates Primary: Anti-HAS1 (TMAB-00829) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 65 kDa Observed band size: 65 kDa |
Application | WB |
Recommended Dose | WB: 1:500-2000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Membrane; Multi-pass membrane protein |
Construction | Hybridoma Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Research Background | HAS1, HAS2 and HAS3 are HA Synthase proteins that synthesize HA (Hyaluronan or hyaluronic acid). The extracellular matrix in most vertebrates express HA, which is a high molecular weight linear polysaccharide composed of alternating glucuronic acid and N-acetylglucosamine residues linked by beta-1,3 and beta-1,4 glycosidic bonds. The three HAS genes show distinct patterns of expression during development and their protein products play significantly different roles in the formation of the HA matrix. Both HAS1 and HAS2 synthesize high molecular weight HA, whereas HAS3 produces lower molecular weight HA. The expression of the three HAS isoforms is more prominent in growing cells than in resting cells and is differentially regulated by various stimuli, suggesting distinct functional roles of the three proteins. HAS1 mRNA shows predominant expression in bone marrow mesenchymal progenitor cells and synovial cells. |
Immunogen | KLH conjugated synthetic peptide: human Hyaluronan synthase 1 |
Antigen Species | Human |
Gene ID | |
Uniprot ID | |
Biology Area | Extracellular Matrix,Stem cells,Axis formation and symmetry,ECM Proteins,Neurogenesis,Other Enzymes |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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