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Haspin-IN-3

Name: Haspin-IN-3
Brand: TargetMol
SKU: T60512
Price: 36 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T60512Cas No. 2416569-95-2

Haspin-IN-3 is a potent haspin inhibitor with an IC50 of 14 nM.Haspin-IN-3 has anticancer activity.

Haspin-IN-3

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Purity: 98.78%

Catalog No. T60512Cas No. 2416569-95-2

Haspin-IN-3 is a potent haspin inhibitor with an IC50 of 14 nM.Haspin-IN-3 has anticancer activity.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$36	-	In Stock
5 mg	$107	-	In Stock
10 mg	$173	-	In Stock
25 mg	$296	-	In Stock
50 mg	$442	-	In Stock
100 mg	$592	-	In Stock
200 mg	$783	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:98.78%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Haspin-IN-3 is a potent haspin inhibitor with an IC50 of 14 nM.Haspin-IN-3 has anticancer activity.
Targets&IC50	Haspin:14 nM
In vitro	Haspin-IN-3 (compound 8l) is a potent haspin inhibitor with an IC50 of 14 nM. Haspin-IN-3 has anticancer effects.[1]

Chemical Properties

Molecular Weight	278.26
Formula	C₁₆H₁₀N₂O₃
Cas No.	2416569-95-2
Smiles	Oc1ccc2C(=O)\C(Oc2c1)=C\c1c[nH]c2ncccc12

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 22.5 mg/mL (80.9 mM), Sonication and heating to 60℃ are recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5938 mL	17.9688 mL	35.9376 mL	179.6881 mL
5 mM	0.7188 mL	3.5938 mL	7.1875 mL	35.9376 mL
10 mM	0.3594 mL	1.7969 mL	3.5938 mL	17.9688 mL
20 mM	0.1797 mL	0.8984 mL	1.7969 mL	8.9844 mL
50 mM	0.0719 mL	0.3594 mL	0.7188 mL	3.5938 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc