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Anti-Phospho-PKCα (Thr638) Antibody (4G731)
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Catalog No. TMAY-01662
Alias PRKACA, p-PKCα (Thr638), p-PKCα (T638), PKCα (p-Thr638), PKCα (p-T638), PKCI+/-, PKC-alpha, PKCalpha, PKCA, PKC α, PKC A, Phospho-PKCα (T638), AAG6
Anti-Phospho-PKCα (Thr638) Antibody (4G731) is a Rabbit antibody targeting Phospho-PKCα (Thr638). Anti-Phospho-PKCα (Thr638) Antibody (4G731) can be used in WB.
Anti-Phospho-PKCα (Thr638) Antibody (4G731)
Anti-Phospho-PKCα (Thr638) Antibody (4G731)
😃Good
Catalog No. TMAY-01662Alias PRKACA, p-PKCα (Thr638), p-PKCα (T638), PKCα (p-Thr638), PKCα (p-T638), PKCI+/-, PKC-alpha, PKCalpha, PKCA, PKC α, PKC A, Phospho-PKCα (T638), AAG6
Anti-Phospho-PKCα (Thr638) Antibody (4G731) is a Rabbit antibody targeting Phospho-PKCα (Thr638). Anti-Phospho-PKCα (Thr638) Antibody (4G731) can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $81 | 7-10 days | |
| 100 μL | $234 | 7-10 days |
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| Description | Anti-Phospho-PKCα (Thr638) Antibody (4G731) is a Rabbit antibody targeting Phospho-PKCα (Thr638). Anti-Phospho-PKCα (Thr638) Antibody (4G731) can be used in WB. |
| Synonyms | PRKACA, p-PKCα (Thr638), p-PKCα (T638), PKCα (p-Thr638), PKCα (p-T638), PKCI+/-, PKC-alpha, PKCalpha, PKCA, PKC α, PKC A, Phospho-PKCα (T638), AAG6 |
| Ig Type | Rabbit IgG |
| Clone | 4G731 |
| Reactivity | Human;
Predicted to React with:>Human Phospho-PKCα (Thr638); Predicted to React with: Species predicted to react based on 100% sequence homology: Mouse, Rat, Cynomolgus, Bovine |
| Specificity | Reacts with: Human
Human Phospho-PKCα (Thr638) Predicted to React with: Species predicted to react based on 100% sequence homology: Mouse, Rat, Cynomolgus, Bovine |
| Verified Activity | 1. Western blot analysis of extracts from HEK-293, untreated (line A); treated with antigen-specific phosphopeptide (line B) or antigen-specific peptide (line C) using Phospho-PKCα (Thr638) Antibody, Rabbit MAb at 1:1000 dilution.
2. Western blot analysis of extracts from HEK-293, using Phospho-PKCα (Thr638) Antibody, Rabbit MAb and other brands’ antibodies (Company C) at dilution of 1:1000 and 1:20000. |
| Application | |
| Recommended Dose | WB: 1:1000-1:5000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with a synthetic phosphopeptide corresponding to residues around Thr638 of human Phospho-PKCα. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5 |
| Research Background | Protein kinase C alpha (PRKCA) is involved in multiple functions and has been implicated in heart failure risks and treatment outcomes. The protein kinase C alpha (PRKCA) gene, coding for a Th17-cell-selective kinase, shows a complex splicing pattern, with at least 2 stable alternative transcripts characterized by an alternative upstream polyadenylation site. Polymorphisms in this gene were associated with several conditions, including multiple sclerosis, asthma, schizophrenia, and cancer. The protein kinase C alpha (PRKCA) gene, encoding a Th17-cell-selective kinase, was repeatedly associated with multiple sclerosis (MS).PRKCA polymorphisms and gene-gene interactions within the ACEi pathway affect the antihypertensive responses to enalapril. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: residues around Thr638 of human Phospho-PKCα. |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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