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Anti-Phospho-PKCα (Thr638) Antibody (4G731) (Synonyms: PRKACA, p-PKCα (Thr638), p-PKCα (T638), PKCα (p-Thr638...)

Catalog No. TMAY-01662 Copy Product Info
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Anti-Phospho-PKCα (Thr638) Antibody (4G731) is a Rabbit antibody targeting Phospho-PKCα (Thr638). Anti-Phospho-PKCα (Thr638) Antibody (4G731) can be used in WB.

Anti-Phospho-PKCα (Thr638) Antibody (4G731)

Copy Product Info
🥰Excellent
Catalog No. TMAY-01662
Synonyms PRKACA, p-PKCα (Thr638), p-PKCα (T638), PKCα (p-Thr638), PKCα (p-T638), PKCI+/-, PKC-alpha, PKCalpha, PKCA, PKC α, PKC A, Phospho-PKCα (T638), AAG6

Anti-Phospho-PKCα (Thr638) Antibody (4G731) is a Rabbit antibody targeting Phospho-PKCα (Thr638). Anti-Phospho-PKCα (Thr638) Antibody (4G731) can be used in WB.

Anti-Phospho-PKCα
(Thr638) Antibody
(4G731)
Pack SizePriceUSA StockGlobal StockQuantity
20 μL$817-10 days7-10 days
100 μL$2347-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-PKCα (Thr638) Antibody (4G731) is a Rabbit antibody targeting Phospho-PKCα (Thr638). Anti-Phospho-PKCα (Thr638) Antibody (4G731) can be used in WB.
SynonymsPRKACA, p-PKCα (Thr638), p-PKCα (T638), PKCα (p-Thr638), PKCα (p-T638), PKCI+/-, PKC-alpha, PKCalpha, PKCA, PKC α, PKC A, Phospho-PKCα (T638), AAG6
Ig Type
Rabbit IgG
Clone
4G731
Reactivity
Human;
Predicted to React with:>Human Phospho-PKCα (Thr638);

Predicted to React with: Species predicted to react based on 100% sequence homology: Mouse, Rat, Cynomolgus, Bovine
Specificity
Reacts with: Human
Human Phospho-PKCα (Thr638)
Predicted to React with: Species predicted to react based on 100% sequence homology: Mouse, Rat, Cynomolgus, Bovine
Verified Activity
1. Western blot analysis of extracts from HEK-293, untreated (line A); treated with antigen-specific phosphopeptide (line B) or antigen-specific peptide (line C) using Phospho-PKCα (Thr638) Antibody, Rabbit MAb at 1:1000 dilution.
2. Western blot analysis of extracts from HEK-293, using Phospho-PKCα (Thr638) Antibody, Rabbit MAb and other brands’ antibodies (Company C) at dilution of 1:1000 and 1:20000.
Application
Recommended Dose
WB: 1:1000-1:5000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with a synthetic phosphopeptide corresponding to residues around Thr638 of human Phospho-PKCα.
PurificationProtein A
AppearanceLiquid
Formulation10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5
Research BackgroundProtein kinase C alpha (PRKCA) is involved in multiple functions and has been implicated in heart failure risks and treatment outcomes. The protein kinase C alpha (PRKCA) gene, coding for a Th17-cell-selective kinase, shows a complex splicing pattern, with at least 2 stable alternative transcripts characterized by an alternative upstream polyadenylation site. Polymorphisms in this gene were associated with several conditions, including multiple sclerosis, asthma, schizophrenia, and cancer. The protein kinase C alpha (PRKCA) gene, encoding a Th17-cell-selective kinase, was repeatedly associated with multiple sclerosis (MS).PRKCA polymorphisms and gene-gene interactions within the ACEi pathway affect the antihypertensive responses to enalapril.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: residues around Thr638 of human Phospho-PKCα.
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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