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Anti-BCL6 Polyclonal Antibody (Synonyms: ZNF51, ZBTB27, LAZ3, BCL6A, BCL5, B-cell CLL/lymphoma 6)

Catalog No. TMAB-00201 Copy Product Info
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Anti-BCL6 Polyclonal Antibody is a Rabbit antibody targeting BCL6. Anti-BCL6 Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P.

Anti-BCL6 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-00201
Synonyms ZNF51, ZBTB27, LAZ3, BCL6A, BCL5, B-cell CLL/lymphoma 6

Anti-BCL6 Polyclonal Antibody is a Rabbit antibody targeting BCL6. Anti-BCL6 Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P.

Anti-BCL6 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3727-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-BCL6 Polyclonal Antibody is a Rabbit antibody targeting BCL6. Anti-BCL6 Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P.
SynonymsZNF51, ZBTB27, LAZ3, BCL6A, BCL5, B-cell CLL/lymphoma 6
Ig Type
IgG
Reactivity
Human,Mouse
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (human lung carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Incubation with (Bcl-6) Polyclonal Antibody, Unconjugated (TMAB-00201) at 1:25 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.
verifiedActivity
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus (By similarity).
Tissue SpecificityExpressed in germinal center T and B-cells and in primary immature dendritic cells.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundThe protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Bcl-6
Antigen Species
Human
Gene Name
BCL6
Gene ID
Protein Name
B-cell lymphoma 6 protein
Uniprot ID
Biology Area
Transcription factors,Proto-oncogenes,Zinc Finger
Function
Transcriptional repressor which is required for germinal center formation and antibody affinity maturation. Probably plays an important role in lymphomagenesis.
Chemical Properties
Molecular WeightTheoretical: 78 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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