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Anti-PTEN Polyclonal Antibody
😃Good
Catalog No. TMAB-01590
Anti-PTEN Polyclonal Antibody is a Rabbit antibody targeting PTEN. Anti-PTEN Polyclonal Antibody can be used in WB.
Anti-PTEN Polyclonal Antibody
Anti-PTEN Polyclonal Antibody
😃Good
Catalog No. TMAB-01590
Anti-PTEN Polyclonal Antibody is a Rabbit antibody targeting PTEN. Anti-PTEN Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $221 | 7-10 days | |
| 100 μL | $372 | 7-10 days | |
| 200 μL | $527 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-PTEN Polyclonal Antibody is a Rabbit antibody targeting PTEN. Anti-PTEN Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Pig) |
| Verified Activity | 25 μg total protein per Lane of various lysates probed with PTEN polyclonal antibody, unconjugated (TMAB-01590) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min. |
| Application | WB |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Nucleus. Nucleus, PML body. Note=Monoubiquitinated form is nuclear. Nonubiquitinated form is cytoplasmic. Colocalized with PML and USP7 in PML nuclear bodies. XIAP/BIRC4 promotes its nuclear localization. |
| Construction | Hybridoma Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | Potential tumor suppressor. Acts as a phosphoinositide3-phosphatase by regulating PtdIns (3,4,5)P3 levels. Involved in regulation of the AKT1 signaling pathway. The unphosphorylated form cooperates with AIP1 to suppress AKT1 activation.The PTEN/MMAC1 discovers the first to have the suppress of the phosphoric acid enzyme activity cancer gene currently.The gene of PTEN locates the chromosome10q23 area, sending forth sex tumor and a few households cancers with the variety to suffer from the comprehensive disease easilyrelevant.The activity that passes to repress the Akt regulates the cell period, the cell ground rule decease and glues to connect.This text discussed PTEN structure, function and its correlationses, the PTEN is in tumor repress function mechanism. |
| Immunogen | KLH conjugated synthetic peptide: human PTEN |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Phosphatases,PTEN pathway,Phosphatases,Tumor Suppressors,Diabetes,Metabolic disorders,Obesity,Lipid Phosphatases |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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