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Synonyms: ZNF515, Zinc finger protein GLIS3, Zinc finger protein 515, NDH, GLI-similar 3, GLIS family zinc finger 3, GLIS 3
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days |
| Description | Anti-GLIS3 Polyclonal Antibody is a Rabbit antibody targeting GLIS3. Anti-GLIS3 Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P,WB. |
| Synonyms | ZNF515, Zinc finger protein GLIS3, Zinc finger protein 515, NDH, GLI-similar 3, GLIS family zinc finger 3, GLIS 3 |
| Ig Type | IgG |
| Reactivity | Human,Rat,Sheep |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nuclear |
| Tissue Specificity | In the adult, expressed at high levels in the kidney and at lower levels in the brain, skeletal muscle, pancreas, liver, lung, thymus and ovary. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein with five C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human GLIS3 |
| Antigen Species | Human |
| Gene Name | GLIS3 |
| Gene ID | |
| Protein Name | Zinc finger protein GLIS3 |
| Uniprot ID | |
| Biology Area | Krueppel like factor,Zinc Finger,Krueppel like factor,Pol II Transcription,Transcription Factors |
| Function | GLIS3 is a member of the GLI similar zinc finger protein family, and encodes a nuclear protein with five C2H2 type zinc finger domains. It functions as both an activator and repressor of transcription, and is specifically involved in the development of pancreatic beta cells, thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full length nature of only two have been determined. |
| Molecular Weight | Theoretical: 84 kDa. Actual: 84 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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