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CXCL13/BCA-1 Protein, Mouse, Recombinant (hFc)

(Synonyms: SCYB13, BLR1L, BLC, BCA-1, BCA1, ANGIE2, ANGIE) Copy Product Info

Synonyms: SCYB13, BLR1L, BLC, BCA-1, BCA1, ANGIE2, ANGIE

Catalog No. TMPK-00734 Copy Product Info
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice. CXCL13/BCA-1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 37.1 kDa and the accession number is O55038.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$56-In Stock
10 µg$88-In Stock
20 µg$143-In Stock
50 µg$278-In Stock
100 µg$465-In Stock
200 µg$8397-10 days7-10 days
500 µg$1,8507-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice. CXCL13/BCA-1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 37.1 kDa and the accession number is O55038.
Species
Mouse
Expression System
HEK293 Cells
TagN-hFc
Accession NumberO55038
ConstructionIle22-Ala109
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationSupplied as 0.22 μm filtered solution in 50 mM Tris, 500 mM NaCl (pH 7.5).
SynonymsSCYB13, BLR1L, BLC, BCA-1, BCA1, ANGIE2, ANGIE
Research Background
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice.
Chemical Properties
Molecular Weight37.1 kDa (predicted). Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
ShippingProteins are shipped with blue ice.
StorageIt is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: CXCL13/BCA-1 Protein, Mouse, Recombinant (hFc) chemical structure | CXCL13/BCA-1 Protein, Mouse, Recombinant (hFc) molecular weight