Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-Phospho-JAK2 (Y1007+Y1008) Antibody (1D853)

😃Good
Catalog No. TMAC-03231

Anti-Phospho-JAK2 (Y1007+Y1008) Antibody (1D853) is a Rabbit antibody targeting Phospho-JAK2 (Y1007+Y1008). Anti-Phospho-JAK2 (Y1007+Y1008) Antibody (1D853) can be used in WB,ICC,IHC,IP.

Anti-Phospho-JAK2 (Y1007+Y1008) Antibody (1D853)

Anti-Phospho-JAK2 (Y1007+Y1008) Antibody (1D853)

😃Good
Catalog No. TMAC-03231
Anti-Phospho-JAK2 (Y1007+Y1008) Antibody (1D853) is a Rabbit antibody targeting Phospho-JAK2 (Y1007+Y1008). Anti-Phospho-JAK2 (Y1007+Y1008) Antibody (1D853) can be used in WB,ICC,IHC,IP.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4987-10 days
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View More

Product Introduction

Bioactivity
Description
Anti-Phospho-JAK2 (Y1007+Y1008) Antibody (1D853) is a Rabbit antibody targeting Phospho-JAK2 (Y1007+Y1008). Anti-Phospho-JAK2 (Y1007+Y1008) Antibody (1D853) can be used in WB,ICC,IHC,IP.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-200; ICC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundJAK2 (Janus Kinase 2) belongs to the emerging family of non-receptor Janus tyrosine kinases, which regulate a spectrum of cellular functions downstream of activated cytokine receptors in the lympho-hematopoietic system. Immuno-logical stimuli, such as interferons and cytokines, induce recruitment of Stat transcription factors to cytokine receptor-associated JAK2. JAK2 then phosphorylates proximal Stat factors, which subsequently dimerize, translocate to the nucleus and bind to cis elements upstream of target gene promoters to regulate transcription. The canonical JAK-Stat pathway is integral to maintaining a normal immune system by stimulating proliferation, differentiation, survival, and host resistance to pathogens. Altering JAK-Stat signaling to reduce cytokine induced pro-inflammatory responses represents an attractive target for inflammatory therapies. Within the JAK2 kinase domain, there is a region that has considerable sequence homology to the regulatory region of the insulin receptor. Among a variety of sites, Tyrosines 1007 and 1008 are sites of trans- or autophosphorylation in vivo and in in vitro kinase reactions.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human JAK2 around the phosphorylation site of Tyr1007 and 1008
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 130 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Anti-Phospho-JAK2 (Y1007+Y1008) Antibody (1D853) | purchase Anti-Phospho-JAK2 (Y1007+Y1008) Antibody (1D853) | Anti-Phospho-JAK2 (Y1007+Y1008) Antibody (1D853) cost | order Anti-Phospho-JAK2 (Y1007+Y1008) Antibody (1D853) | Anti-Phospho-JAK2 (Y1007+Y1008) Antibody (1D853) molecular weight