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Anti-SKP2 Antibody (4A615)
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Catalog No. TMAH-01094 Copy Product Info
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Anti-SKP2 Antibody (4A615) is an antibody targeting SKP2. Anti-SKP2 Antibody (4A615) can be used in ELISA,FCM,IF.
Anti-SKP2 Antibody
(4A615)
(4A615)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $348 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-SKP2 Antibody (4A615) is an antibody targeting SKP2. Anti-SKP2 Antibody (4A615) can be used in ELISA,FCM,IF. |
| Ig Type | Rabbit IgG |
| Clone | 4A615 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IF:1:20-1:200; FCM:1:20-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cytoplasm. Nucleus. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. Degradation of CDKN1B/p27kip also requires CKS1. Recognizes target proteins ORC1, CDT1, RBL2, KMT2A/MLL1, CDK9, RAG2, FOXO1, UBP43, YTHDF2, and probably MYC, TOB1 and TAL1. Degradation of TAL1 also requires STUB1. Recognizes CDKN1A in association with CCNE1 or CCNE2 and CDK2. Promotes ubiquitination and destruction of CDH1 in a CK1-dependent manner, thereby regulating cell migration. Through the ubiquitin-mediated proteasomal degradation of hepatitis C virus non-structural protein 5A, has an antiviral activity towards that virus. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human SKP2 |
| Antigen Species | Human |
| Gene Name | SKP2 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cancer, Cardiovascular, Cell biology |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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