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Daphnoretin

🥰Excellent
Catalog No. T4S1335Cas No. 2034-69-7
Alias Thymelol, Dephnoretin

1. Daphnoretin (Thymelol) has strong antiviral activity, mainly on the later phase of the replication cycle. 2. Daphnoretin has anticancer effects on leukemia, osteosarcoma and uterine cervix cancer cells, might through promoting apoptosis in a mitochondria-mediated way. 3. Daphnoretin causes death of HOS cells by blocking cells successively in G2/M phases and activating the caspase-3 pathway.

Daphnoretin

Daphnoretin

🥰Excellent
Purity: 99.85%
Catalog No. T4S1335Alias Thymelol, DephnoretinCas No. 2034-69-7
1. Daphnoretin (Thymelol) has strong antiviral activity, mainly on the later phase of the replication cycle. 2. Daphnoretin has anticancer effects on leukemia, osteosarcoma and uterine cervix cancer cells, might through promoting apoptosis in a mitochondria-mediated way. 3. Daphnoretin causes death of HOS cells by blocking cells successively in G2/M phases and activating the caspase-3 pathway.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$50In StockIn Stock
10 mg$70In StockIn Stock
25 mg$113In StockIn Stock
50 mg$163In StockIn Stock
100 mg$239In StockIn Stock
1 mL x 10 mM (in DMSO)$48In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.85%
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Product Introduction

Bioactivity
Description
1. Daphnoretin (Thymelol) has strong antiviral activity, mainly on the later phase of the replication cycle. 2. Daphnoretin has anticancer effects on leukemia, osteosarcoma and uterine cervix cancer cells, might through promoting apoptosis in a mitochondria-mediated way. 3. Daphnoretin causes death of HOS cells by blocking cells successively in G2/M phases and activating the caspase-3 pathway.
SynonymsThymelol, Dephnoretin
Chemical Properties
Molecular Weight352.29
FormulaC19H12O7
Cas No.2034-69-7
SmilesCOc1cc2cc(Oc3ccc4ccc(=O)oc4c3)c(=O)oc2cc1O
Relative Density.1.501g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (141.93 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8386 mL14.1929 mL28.3857 mL141.9285 mL
5 mM0.5677 mL2.8386 mL5.6771 mL28.3857 mL
10 mM0.2839 mL1.4193 mL2.8386 mL14.1929 mL
20 mM0.1419 mL0.7096 mL1.4193 mL7.0964 mL
50 mM0.0568 mL0.2839 mL0.5677 mL2.8386 mL
100 mM0.0284 mL0.1419 mL0.2839 mL1.4193 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

Protein kinase CPKCInhibitorinhibitInfluenzaVirusInfluenza VirusDaphnoretinCaspase-3
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