Powder: -20°C for 3 years | In solvent: -80°C for 1 year
33-BCRP inhibitor is a compound that blocks the action of breast cancer resistance protein (BCRP), enhancing the susceptibility of mitoxantrone-resistant H460/MX20 lung cancer cells to the cytotoxic effects of mitoxantrone, both individually and when combined with UV radiation. Additionally, it enhances the sensitivity of KB-C2 epidermal carcinoma cells, which overexpress P-glycoprotein (P-gp) or multidrug resistance protein (MDR), to colchicine-induced apoptosis. Furthermore, at a concentration of 5 µM, it boosts the intracellular accumulation of mitoxantrone in H460/MX20 cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 98.00 | |
5 mg | 35 days | $ 450.00 | |
10 mg | 35 days | $ 798.00 |
Description | 33-BCRP inhibitor is a compound that blocks the action of breast cancer resistance protein (BCRP), enhancing the susceptibility of mitoxantrone-resistant H460/MX20 lung cancer cells to the cytotoxic effects of mitoxantrone, both individually and when combined with UV radiation. Additionally, it enhances the sensitivity of KB-C2 epidermal carcinoma cells, which overexpress P-glycoprotein (P-gp) or multidrug resistance protein (MDR), to colchicine-induced apoptosis. Furthermore, at a concentration of 5 µM, it boosts the intracellular accumulation of mitoxantrone in H460/MX20 cells. |
Synonyms | 33-Breast Cancer Resistance Protein Inhibitor |
Molecular Weight | 339.40 |
Formula | C19H13N7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Soluble
Ethanol: Soluble
Methanol: Soluble
You can also refer to dose conversion for different animals. More
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33-BCRP Inhibitor 33-Breast Cancer Resistance Protein Inhibitor inhibitor inhibit