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Anti-Caspase-6 Antibody (3I701)

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Catalog No. TMAC-00585

Anti-Caspase-6 Antibody (3I701) is a Rabbit antibody targeting Caspase-6. Anti-Caspase-6 Antibody (3I701) can be used in WB,IP.

Anti-Caspase-6 Antibody (3I701)

Anti-Caspase-6 Antibody (3I701)

😃Good
Catalog No. TMAC-00585
Anti-Caspase-6 Antibody (3I701) is a Rabbit antibody targeting Caspase-6. Anti-Caspase-6 Antibody (3I701) can be used in WB,IP.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-Caspase-6 Antibody (3I701) is a Rabbit antibody targeting Caspase-6. Anti-Caspase-6 Antibody (3I701) can be used in WB,IP.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:1000-5000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundA unique family of cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, Ced-3/caspase-1, is comprised of caspase-1, caspase-2, caspase-3, caspase-4, caspase-6, caspase-7 (also designated Mch3, ICE-LAP3 or CMH-1), caspase-9 and caspase-10. Ced-3/caspase-1 family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Poly(ADP-ribose) polymerase plays an integral role in surveying for DNA mutations and double strand breaks. Caspase-3, caspase-7 and caspase-9, but not caspase-1, have been shown to cleave the nuclear protein PARP into an apoptotic fragment. Caspase-6, but not caspase-3, has been shown to cleave the nuclear lamins which are critical to maintaining the integrity of the nuclear envelope and cellular morphology. Caspase-10 has been shown to activate caspase-3 and caspase-7 in response to apoptotic stimuli.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
49099
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 18/33 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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