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CD44 Protein, Human, Recombinant (Avi & mFc), Biotinylated

(Synonyms: Phagocytic glycoprotein I (PGP-I), Phagocytic glycoprotein 1 (PGP-1), MIC4, MDU3, MDU2, LHR, Hyaluronate receptor, HUTCH-I, Hermes antigen, Heparan sulfate proteoglycan, GP90 lymphocyte homing/adhesion receptor, Extracellular matrix receptor III (ECMR-III), Epican, CDw44, CD44 antigen, CD44) Copy Product Info

Synonyms: Phagocytic glycoprotein I (PGP-I), Phagocytic glycoprotein 1 (PGP-1), MIC4, MDU3, MDU2, LHR, Hyaluronate receptor, HUTCH-I, Hermes antigen, Heparan sulfate proteoglycan, GP90 lymphocyte homing/adhesion receptor, Extracellular matrix receptor III (ECMR-III), Epican, CDw44, CD44 antigen, CD44

Catalog No. TMPH-01072 Copy Product Info
CD44 Protein, Human, Recombinant (Avi & mFc), Biotinylated is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 51.0 kDa and the accession number is P16070.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$11520 days20 days
10 µg$18820 days20 days
20 µg$31320 days20 days
50 µg$39620 days20 days
100 µg$49220 days20 days
200 µg$76320 days20 days
500 µg$1,36020 days20 days
1 mg$2,13020 days20 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Measured by its binding ability in a functional ELISA. Immobilized Anti-CD44 Mouse Monoclonal Antibody at 2 μg/mL can bind Biotinylated human CD44, the EC 50 is 2.865-5.099 ng/mL.
Description
CD44 Protein, Human, Recombinant (Avi & mFc), Biotinylated is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 51.0 kDa and the accession number is P16070.
Species
Human
Expression System
HEK293 Cells
TagC-mFc-Avi
Accession NumberP16070
Amino AcidQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIP
Construction21-220 aa
Protein Purity
> 90% as determined by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, 6% Trehalose, pH 7.4
ReconstitutionReconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsPhagocytic glycoprotein I (PGP-I), Phagocytic glycoprotein 1 (PGP-1), MIC4, MDU3, MDU2, LHR, Hyaluronate receptor, HUTCH-I, Hermes antigen, Heparan sulfate proteoglycan, GP90 lymphocyte homing/adhesion receptor, Extracellular matrix receptor III (ECMR-III), Epican, CDw44, CD44 antigen, CD44
Research Background
Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment. Participates thereby in a wide variety of cellular functions including the activation, recirculation and homing of T-lymphocytes, hematopoiesis, inflammation and response to bacterial infection. Engages, through its ectodomain, extracellular matrix components such as hyaluronan/HA, collagen, growth factors, cytokines or proteases and serves as a platform for signal transduction by assembling, via its cytoplasmic domain, protein complexes containing receptor kinases and membrane proteases. Such effectors include PKN2, the RhoGTPases RAC1 and RHOA, Rho-kinases and phospholipase C that coordinate signaling pathways promoting calcium mobilization and actin-mediated cytoskeleton reorganization essential for cell migration and adhesion.
Chemical Properties
Molecular Weight51.0 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: CD44 Protein, Human, Recombinant (Avi & mFc), Biotinylated chemical structure | CD44 Protein, Human, Recombinant (Avi & mFc), Biotinylated molecular weight