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Anti-LRP1 Antibody (9Z880)
😃Good
Catalog No. TMAC-02421
Alias TGFBR5, LRP1A, LRP, KPA, IGFBP3R1, IGFBP-3R, IGFBP3R, DDH3, CD91, APR, APOER, A2MR
Anti-LRP1 Antibody (9Z880) is a Rabbit antibody targeting LRP1. Anti-LRP1 Antibody (9Z880) can be used in WB,ICC/IF,IHC,IP,FCM.
Anti-LRP1 Antibody (9Z880)
Anti-LRP1 Antibody (9Z880)
😃Good
Catalog No. TMAC-02421Alias TGFBR5, LRP1A, LRP, KPA, IGFBP3R1, IGFBP-3R, IGFBP3R, DDH3, CD91, APR, APOER, A2MR
Anti-LRP1 Antibody (9Z880) is a Rabbit antibody targeting LRP1. Anti-LRP1 Antibody (9Z880) can be used in WB,ICC/IF,IHC,IP,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-LRP1 Antibody (9Z880) is a Rabbit antibody targeting LRP1. Anti-LRP1 Antibody (9Z880) can be used in WB,ICC/IF,IHC,IP,FCM. |
| Synonyms | TGFBR5, LRP1A, LRP, KPA, IGFBP3R1, IGFBP-3R, IGFBP3R, DDH3, CD91, APR, APOER, A2MR |
| Ig Type | IgG |
| Clone | 9Z880 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of LRP1 on different lysates using anti-LRP1 antibody at 1/1,000 dilution. Positive control: Lane 1: Mouse liver, Lane 2: Mouse brain Lane, Lane 3: Mouse lung, Lane 4: Human liver, Lane 5: HepG2, Lane 6: Human lung. 2. Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-LRP1 antibody. Counter stained with hematoxylin. 3. ICC staining LRP1 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.. 4. ICC staining LRP1 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. ICC staining LRP1 in HUVEC cells (green). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 6. Flow cytometric analysis of Hela cells with LRP1 antibody at 1/50 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody. |
| Application | |
| Recommended Dose | WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:10-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Members of the LDL receptor gene family, including LDLR (low density lipoprotein receptor), LRP1 (low density lipoprotein related protein), Megalin (also designated GP330), VLDLR (very low density lipoprotein receptor) and ApoER2 are characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. LRP1, also designated LRP and ?-2-Macroglobulin receptor, is an endocytic receptor that mediates the uptake of at least 15 ligands, including ?-2-Macroglobulin and apoE. LRP1 is cleaved into a membrane subunit and an extracellular subunit, which remain non-covalently associated. Proper folding and trafficking of LRP1 is facilitated by the receptor-associated protein (RAP), a molecular chaperone. The uptake of all known ligands through LRP1 can be blocked by RAP, which induces a conformational change in the receptor that renders it unable to bind ligands. LRP1, which is expressed in brain, liver and lung, is also implicated in Alzheimer??s disease (AD), as the human LRP gene localizes to a potential AD locus on chromosome 12. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 85 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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