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Anti-ADRB2 Polyclonal Antibody is a Rabbit antibody targeting ADRB2. Anti-ADRB2 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
| Description | Anti-ADRB2 Polyclonal Antibody is a Rabbit antibody targeting ADRB2. Anti-ADRB2 Polyclonal Antibody can be used in WB. |
| Synonyms | Beta-2 adrenoreceptor, Beta-2 adrenoceptor, Beta-2 adrenergic receptor, B2AR, ADRB2R, ADRB 2 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | Sample: Lane 1: Mouse Heart tissue lysates Lane 2: Mouse Stomach tissue lysates Lane 3: Mouse Cerebrum tissue lysates Lane 4: Rat Heart tissue lysates Lane 5: Rat Stomach tissue lysates Lane 6: Rat Cerebrum tissue lysates Lane 7: Human A431 cell lysates Primary: Anti-TBX1 (TMAB-00070) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 46 kDa Observed band size: 50 kDa ![]() |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. Note=Colocalizes with VHL at the cell membrane. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Beta 2 Adrenergic Receptor is a member of the G protein coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L type calcium channel Ca(V)1.2. This receptor channel complex also contains a G protein, an adenylyl cyclase, cAMP dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein coupled receptor. This gene contains no introns in either its coding or untranslated sequences. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. Expression of the beta 2 Adrenergic Receptor has been reported in adipose, blood, brain, heart, lung, nose, pancreas, skeletal muscle, skin, and vessel. |
| Immunogen | KLH conjugated synthetic peptide: human ADRB2 |
| Antigen Species | Human |
| Gene Name | ADRB2 |
| Gene ID | |
| Protein Name | beta-2 adrenergic receptor |
| Uniprot ID | |
| Biology Area | Ischemia / Reperfusion,Myocardial regeneration,GPCR |
| Function | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. |
| Molecular Weight | Theoretical: 46 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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