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α-Tocopherol phosphate

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Catalog No. T17304Cas No. 38976-17-9
Alias vitamin E phosphate, TocP, alpha-Tocopherol phosphate

α-Tocopherol phosphate disodium salt is a water-soluble derivative of vitamin E that functions as an antioxidant, protecting rat hippocampal neurons against oxidative stress. α-Tocopherol phosphate disodium salt is also used to investigate molecular mechanisms of cellular protection and membrane transport, providing insights into neuroprotection and redox biology.

α-Tocopherol phosphate

α-Tocopherol phosphate

🥰Excellent
Catalog No. T17304Alias vitamin E phosphate, TocP, alpha-Tocopherol phosphateCas No. 38976-17-9
α-Tocopherol phosphate disodium salt is a water-soluble derivative of vitamin E that functions as an antioxidant, protecting rat hippocampal neurons against oxidative stress. α-Tocopherol phosphate disodium salt is also used to investigate molecular mechanisms of cellular protection and membrane transport, providing insights into neuroprotection and redox biology.
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2 mg$30-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
α-Tocopherol phosphate disodium salt is a water-soluble derivative of vitamin E that functions as an antioxidant, protecting rat hippocampal neurons against oxidative stress. α-Tocopherol phosphate disodium salt is also used to investigate molecular mechanisms of cellular protection and membrane transport, providing insights into neuroprotection and redox biology.
In vitro
In the high glucose (Glucose)/ischemia-induced endothelial progenitor cell injury model, treatment with α-Tocopherol phosphate (100 μM) for 24 hours can inhibit the apoptosis process and migration ability of cells. It can also promote the formation of capillary-like tubes by regulating the expression levels of Bcl-2, Akt, NF-κB, p38MAPK, and JNK [2].
In vivo
In the rat type 2 diabetes mellitus and ischemia model induced by Streptozotocin combined with ligation, a single intramuscular injection of 100 μM α-Tocopherol phosphate promotes angiogenesis [2].
Synonymsvitamin E phosphate, TocP, alpha-Tocopherol phosphate
Chemical Properties
Molecular Weight510.69
FormulaC29H51O5P
Cas No.38976-17-9
SmilesCC1=C2C(=C(C)C(OP(=O)(O)O)=C1C)CC[C@](CCC[C@@H](CCC[C@@H](CCCC(C)C)C)C)(C)O2
Relative Density.1.040 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: ≥ 80 mg/mL, Sonication is recommended.
H2O: < 1 mg/mL (insoluble)

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