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α-Tocopherol phosphate disodium salt is a water-soluble derivative of vitamin E that functions as an antioxidant, protecting rat hippocampal neurons against oxidative stress. α-Tocopherol phosphate disodium salt is also used to investigate molecular mechanisms of cellular protection and membrane transport, providing insights into neuroprotection and redox biology.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 2 mg | $30 | - | In Stock |
| Description | α-Tocopherol phosphate disodium salt is a water-soluble derivative of vitamin E that functions as an antioxidant, protecting rat hippocampal neurons against oxidative stress. α-Tocopherol phosphate disodium salt is also used to investigate molecular mechanisms of cellular protection and membrane transport, providing insights into neuroprotection and redox biology. |
| In vitro | In the high glucose (Glucose)/ischemia-induced endothelial progenitor cell injury model, treatment with α-Tocopherol phosphate (100 μM) for 24 hours can inhibit the apoptosis process and migration ability of cells. It can also promote the formation of capillary-like tubes by regulating the expression levels of Bcl-2, Akt, NF-κB, p38MAPK, and JNK [2]. |
| In vivo | In the rat type 2 diabetes mellitus and ischemia model induced by Streptozotocin combined with ligation, a single intramuscular injection of 100 μM α-Tocopherol phosphate promotes angiogenesis [2]. |
| Synonyms | vitamin E phosphate, TocP, alpha-Tocopherol phosphate |
| Molecular Weight | 510.69 |
| Formula | C29H51O5P |
| Cas No. | 38976-17-9 |
| Smiles | CC1=C2C(=C(C)C(OP(=O)(O)O)=C1C)CC[C@](CCC[C@@H](CCC[C@@H](CCCC(C)C)C)C)(C)O2 |
| Relative Density. | 1.040 g/cm3 (Predicted) |
| Color | White |
| Appearance | Solid |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO: ≥ 80 mg/mL, Sonication is recommended. H2O: < 1 mg/mL (insoluble) |
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