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Anti-Phospho-MUSK (Tyr755) Polyclonal Antibody
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Catalog No. TMAC-02694
Anti-Phospho-MUSK (Tyr755) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MUSK (Tyr755). Anti-Phospho-MUSK (Tyr755) Polyclonal Antibody can be used in WB.
Anti-Phospho-MUSK (Tyr755) Polyclonal Antibody
Anti-Phospho-MUSK (Tyr755) Polyclonal Antibody
😃Good
Catalog No. TMAC-02694
Anti-Phospho-MUSK (Tyr755) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MUSK (Tyr755). Anti-Phospho-MUSK (Tyr755) Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $217 | 7-10 days | |
| 100 μL | $316 | 7-10 days |
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Chemical Properties
| Description | Anti-Phospho-MUSK (Tyr755) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MUSK (Tyr755). Anti-Phospho-MUSK (Tyr755) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-1000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Receptor tyrosine kinase which plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between the motor neuron and the skeletal muscle. Recruitment of AGRIN by LRP4 to the MUSK signaling complex induces phosphorylation and activation of MUSK, the kinase of the complex. The activation of MUSK in myotubes regulates the formation of NMJs through the regulation of different processes including the specific expression of genes in subsynaptic nuclei, the reorganization of the actin cytoskeleton and the clustering of the acetylcholine receptors (AChR) in the postsynaptic membrane. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 755(A-D-Y(p)-Y-K) derived from Human MuSK |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 97 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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