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Anti-Phospho-MUSK (Tyr755) Polyclonal Antibody (Synonyms: p-MUSK (Y755), p-MUSK (Tyr755), MUSK (p-Y755), MUSK...)

Catalog No. TMAC-02694 Copy Product Info
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Anti-Phospho-MUSK (Tyr755) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MUSK (Tyr755). Anti-Phospho-MUSK (Tyr755) Polyclonal Antibody can be used in WB.

Anti-Phospho-MUSK (Tyr755) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAC-02694
Synonyms p-MUSK (Y755), p-MUSK (Tyr755), MUSK (p-Y755), MUSK (p-Tyr755)

Anti-Phospho-MUSK (Tyr755) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MUSK (Tyr755). Anti-Phospho-MUSK (Tyr755) Polyclonal Antibody can be used in WB.

Anti-Phospho-MUSK
(Tyr755) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2177-10 days7-10 days
100 μL$3167-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-MUSK (Tyr755) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MUSK (Tyr755). Anti-Phospho-MUSK (Tyr755) Polyclonal Antibody can be used in WB.
Synonymsp-MUSK (Y755), p-MUSK (Tyr755), MUSK (p-Y755), MUSK (p-Tyr755)
Ig Type
IgG
Reactivity
Human
Verified Activity
1. Western blot analysis of extracts from JK cells (Lane 2), using MuSK (Phospho-Tyr755) Antibody TMAC-02694. The lane on the left is treated with antigen-specific peptide.
verifiedActivity
Application
Recommended Dose
WB: 1:500-1000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundReceptor tyrosine kinase which plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between the motor neuron and the skeletal muscle. Recruitment of AGRIN by LRP4 to the MUSK signaling complex induces phosphorylation and activation of MUSK, the kinase of the complex. The activation of MUSK in myotubes regulates the formation of NMJs through the regulation of different processes including the specific expression of genes in subsynaptic nuclei, the reorganization of the actin cytoskeleton and the clustering of the acetylcholine receptors (AChR) in the postsynaptic membrane.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of tyrosine 755(A-D-Y(p)-Y-K) derived from Human MuSK
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 97 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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