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Anti-Phospho-INPP5D (Tyr1020) Antibody (3P963) (Synonyms: p-INPP5D (Y1020), p-INPP5D (Tyr1020), INPP5D (p-Y102...)

Catalog No. TMAC-03264 Copy Product Info
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Anti-Phospho-INPP5D (Tyr1020) Antibody (3P963) is a Rabbit antibody targeting Phospho-INPP5D (Tyr1020). Anti-Phospho-INPP5D (Tyr1020) Antibody (3P963) can be used in ICC,IP,WB.

Anti-Phospho-INPP5D (Tyr1020) Antibody (3P963)

Copy Product Info
🥰Excellent
Catalog No. TMAC-03264
Synonyms p-INPP5D (Y1020), p-INPP5D (Tyr1020), INPP5D (p-Y1020), INPP5D (p-Tyr1020)

Anti-Phospho-INPP5D (Tyr1020) Antibody (3P963) is a Rabbit antibody targeting Phospho-INPP5D (Tyr1020). Anti-Phospho-INPP5D (Tyr1020) Antibody (3P963) can be used in ICC,IP,WB.

Anti-Phospho-INPP5D
(Tyr1020) Antibody
(3P963)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-INPP5D (Tyr1020) Antibody (3P963) is a Rabbit antibody targeting Phospho-INPP5D (Tyr1020). Anti-Phospho-INPP5D (Tyr1020) Antibody (3P963) can be used in ICC,IP,WB.
Synonymsp-INPP5D (Y1020), p-INPP5D (Tyr1020), INPP5D (p-Y1020), INPP5D (p-Tyr1020)
Ig Type
IgG
Clone
3P963
Reactivity
Human
Verified Activity
1. ICC staining Phospho-SHIP (Y1020) in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
2. ICC staining Phospho-SHIP (Y1020) in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining Phospho-SHIP (Y1020) in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
verifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:1000; ICC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe major translational product of the v-Fms oncogene, originally isolated from the McDonough strain of feline sarcoma virus, has been identified as a glycoprotein with intrinsic tyrosine kinase activity. The v-Fms human cellular homolog, c-Fms, has been molecularly cloned and mapped to band q34 on chromosome 5, and identified as the receptor for hematopoietic ligand, CSF-1. Ligand-induced activation of the intrinsic CSF-1R protein tyrosine kinase triggers its interaction with cytoplasmic effector molecules. One such effector molecule, SHIP-1 p145 (SH2-containing-inositol phosphatase), associates with activated Fms. SHIP-1 contains two phosphotyrosine-binding domains (PTB), a unique amino terminal SH2 domain, a proline-rich region, and two highly conserved motifs found among inositol phosphate 5-phosphatases. SHIP-1 displays both phosphatidylinositol 3,4,5-triphosphate and inositol 1,3,4,5-tetrakisphosphate polyphosphate 5-phosphatase activity. Evidence suggests that SHIP-1 may modulate Ras signaling in addition to inositol signaling pathways.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human SHIP around the phosphorylation site of Tyr1020
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 133 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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