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Anti-Phospho-INPP5D (Y1020) Antibody (3P963)

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Catalog No. TMAC-03264

Anti-Phospho-INPP5D (Y1020) Antibody (3P963) is a Rabbit antibody targeting Phospho-INPP5D (Y1020). Anti-Phospho-INPP5D (Y1020) Antibody (3P963) can be used in WB,ICC,IP.

Anti-Phospho-INPP5D (Y1020) Antibody (3P963)

Anti-Phospho-INPP5D (Y1020) Antibody (3P963)

😃Good
Catalog No. TMAC-03264
Anti-Phospho-INPP5D (Y1020) Antibody (3P963) is a Rabbit antibody targeting Phospho-INPP5D (Y1020). Anti-Phospho-INPP5D (Y1020) Antibody (3P963) can be used in WB,ICC,IP.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4987-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-INPP5D (Y1020) Antibody (3P963) is a Rabbit antibody targeting Phospho-INPP5D (Y1020). Anti-Phospho-INPP5D (Y1020) Antibody (3P963) can be used in WB,ICC,IP.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:1000; ICC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe major translational product of the v-Fms oncogene, originally isolated from the McDonough strain of feline sarcoma virus, has been identified as a glycoprotein with intrinsic tyrosine kinase activity. The v-Fms human cellular homolog, c-Fms, has been molecularly cloned and mapped to band q34 on chromosome 5, and identified as the receptor for hematopoietic ligand, CSF-1. Ligand-induced activation of the intrinsic CSF-1R protein tyrosine kinase triggers its interaction with cytoplasmic effector molecules. One such effector molecule, SHIP-1 p145 (SH2-containing-inositol phosphatase), associates with activated Fms. SHIP-1 contains two phosphotyrosine-binding domains (PTB), a unique amino terminal SH2 domain, a proline-rich region, and two highly conserved motifs found among inositol phosphate 5-phosphatases. SHIP-1 displays both phosphatidylinositol 3,4,5-triphosphate and inositol 1,3,4,5-tetrakisphosphate polyphosphate 5-phosphatase activity. Evidence suggests that SHIP-1 may modulate Ras signaling in addition to inositol signaling pathways.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human SHIP around the phosphorylation site of Tyr1020
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 133 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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