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Anti-Phospho-INPP5D (Tyr1020) Antibody (3P963)
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Catalog No. TMAC-03264
Alias p-INPP5D (Y1020), p-INPP5D (Tyr1020), INPP5D (p-Y1020), INPP5D (p-Tyr1020)
Anti-Phospho-INPP5D (Tyr1020) Antibody (3P963) is a Rabbit antibody targeting Phospho-INPP5D (Tyr1020). Anti-Phospho-INPP5D (Tyr1020) Antibody (3P963) can be used in ICC,IP,WB.
Anti-Phospho-INPP5D (Tyr1020) Antibody (3P963)
Anti-Phospho-INPP5D (Tyr1020) Antibody (3P963)
😃Good
Catalog No. TMAC-03264Alias p-INPP5D (Y1020), p-INPP5D (Tyr1020), INPP5D (p-Y1020), INPP5D (p-Tyr1020)
Anti-Phospho-INPP5D (Tyr1020) Antibody (3P963) is a Rabbit antibody targeting Phospho-INPP5D (Tyr1020). Anti-Phospho-INPP5D (Tyr1020) Antibody (3P963) can be used in ICC,IP,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $498 | 7-10 days |
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| Description | Anti-Phospho-INPP5D (Tyr1020) Antibody (3P963) is a Rabbit antibody targeting Phospho-INPP5D (Tyr1020). Anti-Phospho-INPP5D (Tyr1020) Antibody (3P963) can be used in ICC,IP,WB. |
| Synonyms | p-INPP5D (Y1020), p-INPP5D (Tyr1020), INPP5D (p-Y1020), INPP5D (p-Tyr1020) |
| Ig Type | IgG |
| Clone | 3P963 |
| Reactivity | Human |
| Verified Activity | 1. ICC staining Phospho-SHIP (Y1020) in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 2. ICC staining Phospho-SHIP (Y1020) in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining Phospho-SHIP (Y1020) in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| Application | |
| Recommended Dose | WB: 1:1000; ICC: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The major translational product of the v-Fms oncogene, originally isolated from the McDonough strain of feline sarcoma virus, has been identified as a glycoprotein with intrinsic tyrosine kinase activity. The v-Fms human cellular homolog, c-Fms, has been molecularly cloned and mapped to band q34 on chromosome 5, and identified as the receptor for hematopoietic ligand, CSF-1. Ligand-induced activation of the intrinsic CSF-1R protein tyrosine kinase triggers its interaction with cytoplasmic effector molecules. One such effector molecule, SHIP-1 p145 (SH2-containing-inositol phosphatase), associates with activated Fms. SHIP-1 contains two phosphotyrosine-binding domains (PTB), a unique amino terminal SH2 domain, a proline-rich region, and two highly conserved motifs found among inositol phosphate 5-phosphatases. SHIP-1 displays both phosphatidylinositol 3,4,5-triphosphate and inositol 1,3,4,5-tetrakisphosphate polyphosphate 5-phosphatase activity. Evidence suggests that SHIP-1 may modulate Ras signaling in addition to inositol signaling pathways. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | A synthesized phosphopeptide: human SHIP around the phosphorylation site of Tyr1020 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 133 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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