Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-MDM2 Antibody (6Z692)

😃Good
Catalog No. TMAC-02509

Anti-MDM2 Antibody (6Z692) is a Mouse antibody targeting MDM2. Anti-MDM2 Antibody (6Z692) can be used in WB,IP,IF,IHC-P.

Anti-MDM2 Antibody (6Z692)

Anti-MDM2 Antibody (6Z692)

😃Good
Catalog No. TMAC-02509
Anti-MDM2 Antibody (6Z692) is a Mouse antibody targeting MDM2. Anti-MDM2 Antibody (6Z692) can be used in WB,IP,IF,IHC-P.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4267-10 days
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View More

Product Introduction

Bioactivity
Description
Anti-MDM2 Antibody (6Z692) is a Mouse antibody targeting MDM2. Anti-MDM2 Antibody (6Z692) can be used in WB,IP,IF,IHC-P.
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:100-1000; IHC-P: 1:50-500; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research Backgroundp53 is the most commonly mutated gene in human cancer identified to date. Expression of p53 leads to inhibition of cell growth by preventing progression of cells from G1 to S phase of the cell cycle. Most importantly, p53 functions to cause arrest of cells in the G1 phase of the cell cycle following any exposure of cells to DNA-damaging agents. The MDM2 (murine double minute-2) protein was initially identified as an oncogene in a murine transformation system. MDM2 functions to bind p53 and block p53-mediated transactivation of cotransfected reporter constructs. The MDM2 gene is amplified in a high percentage of human sarcomas that retain wildtype p53 and tumor cells that overexpress MDM2 can tolerate high levels of p53 expression. These findings argue that MDM2 overexpression represents at least one mechanism by which p53 function can be abrogated during tumorigenesis.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Amino acids 154-167 of MDM2 of human origin
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 90 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Anti-MDM2 Antibody (6Z692) | purchase Anti-MDM2 Antibody (6Z692) | Anti-MDM2 Antibody (6Z692) cost | order Anti-MDM2 Antibody (6Z692) | Anti-MDM2 Antibody (6Z692) molecular weight