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Synonyms: AMPKG3
Anti-PRKAG3 Monoclonal Antibody
(4Q707)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 µL | $298 | 7-10 days | 7-10 days | |
| 100 µL | $426 | 7-10 days | 7-10 days |
| Description | Anti-PRKAG3 Monoclonal Antibody (4Q707) is a Mouse antibody targeting PRKAG3. Anti-PRKAG3 Monoclonal Antibody (4Q707) can be used in IHC,IF. |
| Synonyms | AMPKG3 |
| Ig Type | IgG1 |
| Clone | 4Q707 |
| Reactivity | Human |
| Verified Activity | 1. Immunohistochemical analysis of paraffin-embedded human rectum tissue using anti-PRKAG3 antibody. Counter stained with hematoxylin. 2. ICC staining PRKAG3 (green) and Actin filaments (red) in Hela cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. ,![]() |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; IF: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human PRKAG3 (AA: 9-151) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | PRKAG3 |
| Gene ID | |
| Protein Name | 5'-AMP-activated protein kinase subunit gamma-3 |
| Uniprot ID |
| Molecular Weight | Theoretical: 54 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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