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Anti-PRKAG3 Antibody (6D439)

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Catalog No. TMAC-03423

Anti-PRKAG3 Antibody (6D439) is a Mouse antibody targeting PRKAG3. Anti-PRKAG3 Antibody (6D439) can be used in WB,ICC,IHC.

Anti-PRKAG3 Antibody (6D439)

Anti-PRKAG3 Antibody (6D439)

😃Good
Catalog No. TMAC-03423
Anti-PRKAG3 Antibody (6D439) is a Mouse antibody targeting PRKAG3. Anti-PRKAG3 Antibody (6D439) can be used in WB,ICC,IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4267-10 days
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Product Introduction

Bioactivity
Description
Anti-PRKAG3 Antibody (6D439) is a Mouse antibody targeting PRKAG3. Anti-PRKAG3 Antibody (6D439) can be used in WB,ICC,IHC.
Reactivity
Human
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-200; ICC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundAMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enz
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 54 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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