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Anti-Prohibitin Antibody (1C561)
(Synonyms: Prohibitin 1, Phb1, Phb, B-cell receptor-associated protein 32 (BAP 32)) Copy Product Info
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Synonyms: Prohibitin 1, Phb1, Phb, B-cell receptor-associated protein 32 (BAP 32)
Catalog No. TMAC-03437 Copy Product Info
🥰Excellent
Anti-Prohibitin Antibody (1C561) is a Rabbit antibody targeting Prohibitin. Anti-Prohibitin Antibody (1C561) can be used in FCM,ICC,IHC,IP,WB.
Anti-Prohibitin Antibody
(1C561)
(1C561)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $298 | 7-10 days | 7-10 days | |
| 100 μL | $496 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
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Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-Prohibitin Antibody (1C561) is a Rabbit antibody targeting Prohibitin. Anti-Prohibitin Antibody (1C561) can be used in FCM,ICC,IHC,IP,WB. |
| Synonyms | Prohibitin 1, Phb1, Phb, B-cell receptor-associated protein 32 (BAP 32) |
| Ig Type | IgG |
| Clone | 1C561 |
| Reactivity | Human,Mouse,Rat,zebrafish |
| Application | |
| Recommended Dose | WB: 1:1000-2000; IHC: 1:200-500; ICC: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Prohibitin is an evolutionarily conserved protein that has antiproliferative activity. The gene encoding human prohibitin maps to chromosome 17q21 and is ubiquitously expressed. Prohibitin is a post-synthetically modified protein that is localized in the inner membrane of mitochondria, where it regulates the cell cycle by blocking the transition between the G1 and S phases, and on the plasma membrane of B cells, where it mediates B cell maturation. Prohibitin mRNA and protein levels are high in G1, decline during the S phase, rise again in G2 and decline in M phase, which suggests that prohibitin controls the cell cycle by using both transcriptional and posttranslational mechanisms. Prohibitin is also a potential tumor suppressor protein that binds to retinoblastoma (Rb) and subsequently inhibits the activity of E2F family members in response to specific signaling cascades. Prohibitin 2 is a repressor of estrogen receptor activity, and is required for somatic and germline differentiation in the larval gonad during embryonic development. Mutations in the Prohibitin genes are correlated with breast cancer development and/or progressionin more than 80% of the cell lines analyzed. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 30 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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