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Kaempferol-7-O-rhamnoside

Name: Kaempferol-7-O-rhamnoside
Brand: TargetMol
SKU: TN1827
Price: 98 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN1827Cas No. 20196-89-8

Alias Kaempferol 7-O-rhamnoside

Kaempferol-7-O-rhamnoside is a natural product discovered in Siraitia grosvenori, exhibiting μM-level inhibitory effects against HCT-116 and SMMC-7721.

Kaempferol-7-O-rhamnoside

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Purity: 99.95%

Catalog No. TN1827Alias Kaempferol 7-O-rhamnosideCas No. 20196-89-8

Kaempferol-7-O-rhamnoside is a natural product discovered in Siraitia grosvenori, exhibiting μM-level inhibitory effects against HCT-116 and SMMC-7721.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$98	-	In Stock
5 mg	$265	-	In Stock
10 mg	$397	-	In Stock
25 mg	$675	-	In Stock
50 mg	$959	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.95%

Appearance:Solid

Color:Yellow

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Kaempferol-7-O-rhamnoside is a natural product discovered in Siraitia grosvenori, exhibiting μM-level inhibitory effects against HCT-116 and SMMC-7721.
In vitro	Kaempferol-7-O-rhamnoside (100-500 μM) exhibited no significant cytotoxicity on H9c2 cardiomyocytes and could antagonize H2O2-induced cell damage while improving cell viability [2]. Kaempferol-7-O-rhamnoside (100-500 μM) concentration-dependently upregulated the mRNA expression of AMPKα1 in H9c2 cardiomyocytes [2]. Kaempferol-7-O-rhamnoside (25-100 μM, 24 hours) inhibited the activities of AST and AKP in APAP-induced L02 cells [3]. Kaempferol-7-O-rhamnoside (100 μM, 24 hours) significantly reduced ROS generation in APAP-induced L02 cells [3]. Kaempferol-7-O-rhamnoside (25-100 μmol/L, 24 hours) significantly upregulated the mRNA expression of FXR and downregulated the mRNA expression of Cyp7a1 in APAP-induced L02 cells [3].
Synonyms	Kaempferol 7-O-rhamnoside

Chemical Properties

Molecular Weight	432.38
Formula	C₂₁H₂₀O₁₀
Cas No.	20196-89-8
Smiles	O=C1C=2C(OC(=C1O)C3=CC=C(O)C=C3)=CC(O[C@H]4[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O4)=CC2O
Relative Density.	no data available

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (185.02 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3128 mL	11.5639 mL	23.1278 mL	115.6390 mL
5 mM	0.4626 mL	2.3128 mL	4.6256 mL	23.1278 mL
10 mM	0.2313 mL	1.1564 mL	2.3128 mL	11.5639 mL
20 mM	0.1156 mL	0.5782 mL	1.1564 mL	5.7820 mL
50 mM	0.0463 mL	0.2313 mL	0.4626 mL	2.3128 mL
100 mM	0.0231 mL	0.1156 mL	0.2313 mL	1.1564 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc