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Mucin-1/MUC1 Protein, Human, Recombinant (Isoform Y, hFc)
(Synonyms: PUM, PEMT, PEM, Mucin-1, Mucin1, MUC1/Y, MUC-1, MUC1, KL-6, H23AG, Episialin, EMA, CD227, CA 15-3) Copy Product InfoSynonyms: PUM, PEMT, PEM, Mucin-1, Mucin1, MUC1/Y, MUC-1, MUC1, KL-6, H23AG, Episialin, EMA, CD227, CA 15-3
Catalog No. TMPK-00828 Copy Product Info
MUC1, the transmembrane glycoprotein Mucin 1, is usually found to be overexpressed in a variety of epithelial cancers playing an important role in disease progression. MUC1 isoforms such as MUC1/Y, which lacks the entire variable number of tandem repeat region, are involved in oncogenic processes by enhancing tumour initiation. MUC1/Y is therefore considered a promising target for the identification and treatment of epithelial cancers.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $68 | - | In Stock | |
| 10 µg | $108 | - | In Stock | |
| 20 µg | $177 | - | In Stock | |
| 50 µg | $346 | 7-10 days | 7-10 days | |
| 100 µg | $581 | - | In Stock | |
| 200 µg | $1,050 | 7-10 days | 7-10 days | |
| 500 µg | $2,330 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | MUC1, the transmembrane glycoprotein Mucin 1, is usually found to be overexpressed in a variety of epithelial cancers playing an important role in disease progression. MUC1 isoforms such as MUC1/Y, which lacks the entire variable number of tandem repeat region, are involved in oncogenic processes by enhancing tumour initiation. MUC1/Y is therefore considered a promising target for the identification and treatment of epithelial cancers. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-hFc |
| Accession Number | P15941-7 |
| Construction | Ser24-Gly158 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | PUM, PEMT, PEM, Mucin-1, Mucin1, MUC1/Y, MUC-1, MUC1, KL-6, H23AG, Episialin, EMA, CD227, CA 15-3 |
| Research Background | MUC1, the transmembrane glycoprotein Mucin 1, is usually found to be overexpressed in a variety of epithelial cancers playing an important role in disease progression. MUC1 isoforms such as MUC1/Y, which lacks the entire variable number of tandem repeat region, are involved in oncogenic processes by enhancing tumour initiation. MUC1/Y is therefore considered a promising target for the identification and treatment of epithelial cancers. |
| Molecular Weight | 41.38 kDa (predicted). Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: Mucin-1/MUC1 Protein, Human, Recombinant (Isoform Y, hFc) chemical structure | Mucin-1/MUC1 Protein, Human, Recombinant (Isoform Y, hFc) molecular weight
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