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Anti-USP14 Antibody (2P900)

(Synonyms: USP 14, Ubiquitin-specific-processing protease 14, Ubiquitin thioesterase 14, Ubiquitin carboxyl-terminal hydrolase 14, TGT, EC 3.4.19.12, Deubiquitinating enzyme 14) Copy Product Info
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Synonyms: USP 14, Ubiquitin-specific-processing protease 14, Ubiquitin thioesterase 14, Ubiquitin carboxyl-terminal hydrolase 14, TGT, EC 3.4.19.12, Deubiquitinating enzyme 14

Catalog No. TMAH-01236 Copy Product Info
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Anti-USP14 Antibody (2P900) is an antibody targeting USP14. Anti-USP14 Antibody (2P900) can be used in ELISA,IF,WB.
Anti-USP14 Antibody
(2P900)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2077-10 days7-10 days
100 μL$3487-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-USP14 Antibody (2P900) is an antibody targeting USP14. Anti-USP14 Antibody (2P900) can be used in ELISA,IF,WB.
SynonymsUSP 14, Ubiquitin-specific-processing protease 14, Ubiquitin thioesterase 14, Ubiquitin carboxyl-terminal hydrolase 14, TGT, EC 3.4.19.12, Deubiquitinating enzyme 14
Ig Type
Rabbit IgG
Clone
2P900
Reactivity
Human
Application
Recommended Dose
WB:1:500-1:2000; IF:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationCytoplasm. Cell membrane; Peripheral membrane protein.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundProteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs). Plays a role in the innate immune defense against viruses by stabilizing the viral DNA sensor CGAS and thus inhibiting its autophagic degradation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human USP14
Antigen Species
Human
Gene Name
USP14
Gene ID
Uniprot ID
Biology Area
Epigenetics and Nuclear Signaling, Cell biology
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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