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IL-21 Protein, Mouse, Recombinant
(Synonyms: interleukin 21, IL-21) Copy Product InfoSynonyms: interleukin 21, IL-21
Catalog No. TMPY-02806 Copy Product Info
Purity: 96.1%
IL-21 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 14.3kDa and the accession number is Q9ES17.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $98 | 7-10 days | 7-10 days | |
| 10 μg | $166 | 7-10 days | 7-10 days | |
| 20 μg | $275 | - | In Stock | |
| 50 μg | $597 | 7-10 days | 7-10 days | |
| 100 μg | $1,080 | 7-10 days | 7-10 days | |
| 200 μg | $1,970 | 7-10 days | 7-10 days | |
| 500 μg | $4,380 | 7-10 days | 7-10 days | |
| 1 mg | $8,080 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
Batch Information
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Purity:96.1%
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Measured by its ability to induce Interferon gamma secretion by human natural killer lymphoma NK-92 cells. The ED50 for this effect is typically 10-65 ng/mL. |
| Description | IL-21 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 14.3kDa and the accession number is Q9ES17. |
| Species | Mouse |
| Expression System | E. coli |
| Tag | Tag Free |
| Accession Number | Q9ES17 |
| Construction | A DNA sequence encoding the soluble form of mouse IL21 (Q9ES17) (Pro 25-Ser 146) was expressed, with an initial Met at the N-terminus. Predicted N terminal: Met |
| Protein Purity | ≥ 95 % as determined by SDS-PAGE |
| Endotoxin | Please contact us for more information. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.5. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | interleukin 21, IL-21 |
| Research Background | IL21 belongs to the IL-15/IL-21 family. It is a cytokine with immunoregulatory activity. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. IL21 is expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes. It may promote the transition between innate and adaptive immunity. IL-21 has been tried as a therapy for alleviating allergic responses. It can significantly decrease pro-inflammatory cytokines produced by T cells in addition to decreasing IgE levels in a mouse model for rhinitis (nasal passage inflammation).Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Molecular Weight | 14.3kDa (predicted); 15 kDa (reducing conditions) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: IL-21 Protein, Mouse, Recombinant chemical structure | IL-21 Protein, Mouse, Recombinant molecular weight
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