TRAIL R3/TNFRSF10C Protein, Human, Recombinant (hFc & His)

Name: TRAIL R3/TNFRSF10C Protein, Human, Recombinant (hFc & His)
Brand: TargetMol
SKU: TMPJ-00418
Rating: 4.5 (1 reviews)

(Synonyms: Tumor Necrosis Factor Receptor Superfamily Member 10C, TRAIL Re, TNF-Related Apoptosis-Inducing Ligand Receptor 3, Lymphocyte Inhibitor of TRAIL, Decoy TRAIL Receptor Without Death Domain, Decoy Receptor 1, DcR1, Antagonist Decoy Receptor for TRAIL/Apo-2L) Copy Product Info

Synonyms: Tumor Necrosis Factor Receptor Superfamily Member 10C, TRAIL Re, TNF-Related Apoptosis-Inducing Ligand Receptor 3, Lymphocyte Inhibitor of TRAIL, Decoy TRAIL Receptor Without Death Domain, Decoy Receptor 1, DcR1, Antagonist Decoy Receptor for TRAIL/Apo-2L

Catalog No. TMPJ-00418 Copy Product Info

Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C) is a glycosyl-phosphatidylinositol-linked membrane protein which binds TRAIL with high affinity. TNFRSF10C has the TRAIL-binding extracellular cysteine-rich domains, lacks the intracellular signaling domain. As a result, binding of TRAIL to TRAIL R3 doesn't transduce an apoptosis signal. The expression of TRAIL R3 gene has been shown to protect cells bearing TRAIL R1 and/or TRAIL R2 from TRAIL-induced apoptosis.

TRAIL R3/TNFRSF10C Protein, Human, Recombinant (hFc & His)

Pack Size	Price	USA Stock	Global Stock
5 µg	$39	35 days	35 days
10 µg	$60	35 days	35 days
20 µg	$96	35 days	35 days
50 µg	$183	35 days	35 days
100 µg	$285	35 days	35 days
200 µg	$445	35 days	35 days
500 µg	$806	35 days	35 days
1 mg	$1,060	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C) is a glycosyl-phosphatidylinositol-linked membrane protein which binds TRAIL with high affinity. TNFRSF10C has the TRAIL-binding extracellular cysteine-rich domains, lacks the intracellular signaling domain. As a result, binding of TRAIL to TRAIL R3 doesn't transduce an apoptosis signal. The expression of TRAIL R3 gene has been shown to protect cells bearing TRAIL R1 and/or TRAIL R2 from TRAIL-induced apoptosis.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc-6xHis
Accession Number	O14798
Amino Acid	Ala26-Ala221
Construction	Ala26-Ala221
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Tumor Necrosis Factor Receptor Superfamily Member 10C, TRAIL Re, TNF-Related Apoptosis-Inducing Ligand Receptor 3, Lymphocyte Inhibitor of TRAIL, Decoy TRAIL Receptor Without Death Domain, Decoy Receptor 1, DcR1, Antagonist Decoy Receptor for TRAIL/Apo-2L
Research Background	Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C) is a glycosyl-phosphatidylinositol-linked membrane protein which binds TRAIL with high affinity. TNFRSF10C has the TRAIL-binding extracellular cysteine-rich domains, lacks the intracellular signaling domain. As a result, binding of TRAIL to TRAIL R3 doesn’t transduce an apoptosis signal. The expression of TRAIL R3 gene has been shown to protect cells bearing TRAIL R1 and/or TRAIL R2 from TRAIL-induced apoptosis.

Chemical Properties

Molecular Weight

90 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: TRAIL R3/TNFRSF10C Protein, Human, Recombinant (hFc & His) chemical structure | TRAIL R3/TNFRSF10C Protein, Human, Recombinant (hFc & His) molecular weight