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ALK Protein, Mouse, Recombinant (hFc)
(Synonyms: CD246, Anaplastic lymphoma kinase, ALK tyrosine kinase receptor) Copy Product InfoSynonyms: CD246, Anaplastic lymphoma kinase, ALK tyrosine kinase receptor
Catalog No. TMPK-00927 Copy Product Info
Anaplastic lymphoma kinase (ALK) is mostly known for its oncogenic role in several human cancers. Recent evidences clearly indicate new roles of ALK and its genetic aberrations (e.g. gene rearrangements and mutations) in immune evasion, innate and cell-mediated immunity. New ALK-related immunotherapy approaches are demonstrating both preclinical and clinical promises.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $48 | 7-10 days | 7-10 days | |
| 10 μg | $76 | 7-10 days | 7-10 days | |
| 20 μg | $122 | 7-10 days | 7-10 days | |
| 50 μg | $236 | 7-10 days | 7-10 days | |
| 100 μg | $393 | 7-10 days | 7-10 days | |
| 200 μg | $712 | 7-10 days | 7-10 days | |
| 500 μg | $1,570 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Anaplastic lymphoma kinase (ALK) is mostly known for its oncogenic role in several human cancers. Recent evidences clearly indicate new roles of ALK and its genetic aberrations (e.g. gene rearrangements and mutations) in immune evasion, innate and cell-mediated immunity. New ALK-related immunotherapy approaches are demonstrating both preclinical and clinical promises. |
| Species | Mouse |
| Expression System | HEK293 Cells |
| Tag | C-hFc |
| Accession Number | P97793 |
| Construction | Ser19-Cys692 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as 0.22 μm filtered solution in PBS, 10% Glycerol (pH 7.4). |
| Stability & Storage | It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Proteins are shipped with blue ice. |
| Synonyms | CD246, Anaplastic lymphoma kinase, ALK tyrosine kinase receptor |
| Research Background |
| Molecular Weight | 101.11 kDa (predicted). Due to glycosylation, the protein migrates to 115-125 kDa based on Tris-Bis PAGE result. |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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You can also refer to dose conversion for different animals. More Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: ALK Protein, Mouse, Recombinant (hFc) chemical structure | ALK Protein, Mouse, Recombinant (hFc) molecular weight
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