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Bromo-PEG1-CH2-Boc is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 7-10 days | |
500 mg | Inquiry | 7-10 days |
Description | Bromo-PEG1-CH2-Boc is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins by containing two ligands connected by a linker: one for an E3 ubiquitin ligase and the other for the target protein [1]. |
Molecular Weight | 239.11 |
Formula | C8H15BrO3 |
Cas No. | 157759-50-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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