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Anti-Claudin-2 Polyclonal Antibody (Synonyms: SP82, SP 82, OTTHUMP00000023793, CLDN2, CLDN 2, CLD2, Claudi...)

Catalog No. TMAB-00441 Copy Product Info
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Anti-Claudin-2 Polyclonal Antibody is a Rabbit antibody targeting Claudin-2. Anti-Claudin-2 Polyclonal Antibody can be used in WB.

Anti-Claudin-2 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-00441
Synonyms SP82, SP 82, OTTHUMP00000023793, CLDN2, CLDN 2, CLD2, Claudin2

Anti-Claudin-2 Polyclonal Antibody is a Rabbit antibody targeting Claudin-2. Anti-Claudin-2 Polyclonal Antibody can be used in WB.

Anti-Claudin-2 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5287-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Claudin-2 Polyclonal Antibody is a Rabbit antibody targeting Claudin-2. Anti-Claudin-2 Polyclonal Antibody can be used in WB.
SynonymsSP82, SP 82, OTTHUMP00000023793, CLDN2, CLDN 2, CLD2, Claudin2
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)
Verified Activity
Sample:
A549 (Human) Cell Lysate at 30 μg
Primary: Anti-Claudin 2 (TMAB-00441) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 25 kDa
Observed band size: 25 kDa
verifiedActivity
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell junction; tight junction. Cell membrane.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundThe claudin superfamily consists of structurally related proteins that are important structural and functional components of tight junctions. Claudin-2, also known as CLDN2 or SP82, is a 230 amino acid multi-pass membrane protein that localizes to the cell junctions and belongs to the claudin superfamily. Able to form homopolymers of heteropolymers with other claudin family members, claudin-2 plays an essential role in mediating calcium-independent cell-adhesion activity that is necessary for tight junction-specific obliteration of the intercellular space. Overexpression of claudin-2 is associated with a variety of diseases, including lung cancer, colorectal cancer, gastrointestinal carcinomas and inflammatory bowel disease, further affirming the importance of claudin-2 in cell adhesion. The gene encoding claudin-2 maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Claudin 2
Antigen Species
Human
Gene Name
CLDN2
Gene ID
Protein Name
Claudin-2
Uniprot ID
Biology Area
Tight Junctions
Function
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Chemical Properties
Molecular WeightTheoretical: 25 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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