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Anti-Myosin-6/MYH6 Polyclonal Antibody
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Catalog No. TMAB-00842
Alias Myosin heavy polypeptide 7 cardiac muscle beta, Myosin heavy chain cardiac muscle beta isoform, Myosin heavy chain cardiac muscle alpha isoform, MyHC-β, MyHC-α, MyHC-beta, MYHCB, MyHC-alpha, MYHCA, MYHC B, MYHC A, MYHC, MYH7, MYH6+MYH7, MYH6/MYH7, MYH6, MYH 7, MYH 6, MPD1, MGC138378, MGC138376, heavy chain cardiac Myosin, CMH1, CMD1S, ASD3, alpha MHC
Anti-Myosin-6/MYH6 Polyclonal Antibody is a Rabbit antibody targeting heavy chain cardiac Myosin. Anti-Myosin-6/MYH6 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
Anti-Myosin-6/MYH6 Polyclonal Antibody
Anti-Myosin-6/MYH6 Polyclonal Antibody
😃Good
Catalog No. TMAB-00842Alias Myosin heavy polypeptide 7 cardiac muscle beta, Myosin heavy chain cardiac muscle beta isoform, Myosin heavy chain cardiac muscle alpha isoform, MyHC-β, MyHC-α, MyHC-beta, MYHCB, MyHC-alpha, MYHCA, MYHC B, MYHC A, MYHC, MYH7, MYH6+MYH7, MYH6/MYH7, MYH6, MYH 7, MYH 6, MPD1, MGC138378, MGC138376, heavy chain cardiac Myosin, CMH1, CMD1S, ASD3, alpha MHC
Anti-Myosin-6/MYH6 Polyclonal Antibody is a Rabbit antibody targeting heavy chain cardiac Myosin. Anti-Myosin-6/MYH6 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Myosin-6/MYH6 Polyclonal Antibody is a Rabbit antibody targeting heavy chain cardiac Myosin. Anti-Myosin-6/MYH6 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P. |
| Synonyms | Myosin heavy polypeptide 7 cardiac muscle beta, Myosin heavy chain cardiac muscle beta isoform, Myosin heavy chain cardiac muscle alpha isoform, MyHC-β, MyHC-α, MyHC-beta, MYHCB, MyHC-alpha, MYHCA, MYHC B, MYHC A, MYHC, MYH7, MYH6+MYH7, MYH6/MYH7, MYH6, MYH 7, MYH 6, MPD1, MGC138378, MGC138376, heavy chain cardiac Myosin, CMH1, CMD1S, ASD3, alpha MHC |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Chicken,Dog,Pig,Cow,Rabbit) |
| Verified Activity | Tissue/cell: rat kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-SM-MHC Polyclonal Antibody, Unconjugated (TMAB-00842) 1:400, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm, myofibril. Note=Thick filaments of the myofibrils. |
| Tissue Specificity | Both wild type and variant Gln-403 are detected in skeletal muscle (at protein level). |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Myosin heavy chains are ubiquitous Actin-based motor proteins that convert the chemical energy derived from ATP hydrolysis into the mechanical energy that drives diverse motile processes in eukaryotic cells, including cytokinesis, vesicular transport and cellular locomotion. Muscle myosin is a heterohexamer consisting of two myosin heavy chains and two associated nonidentical pairs of myosin light chains. The seven myosin heavy chain isoforms that predominate in mammalian skeletal muscles include two developmental isoforms, MHC-embryonic (MYH3) and MHC-perinatal (MYH8); three adult skeletal muscle isoforms, MHC IIa (MYH2), MHC IIb (MYH4) and MHC IIx/d (MYH1); and MHC-∫/slow (MYH7 or MHC-∫), which is also expressed in cardiac muscle. Research indicates that mutations of the MYH7 gene causes hypertrophic cardiomyopathy. |
| Immunogen | KLH conjugated synthetic peptide: the middle of human MyHC-beta |
| Antigen Species | Human |
| Gene Name | MYH7 |
| Gene ID | |
| Protein Name | Myosin-7 |
| Uniprot ID | |
| Biology Area | Myosins,Autoimmune,Myosin |
| Function | Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. |
| Molecular Weight | Theoretical: 213 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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