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Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His)
(Synonyms: Transforming growth factor β-1, Transforming growth factor beta-1 proprotein, TGFβ-1, TGFB1, TGFB, Latent TGF-β1) Copy Product InfoSynonyms: Transforming growth factor β-1, Transforming growth factor beta-1 proprotein, TGFβ-1, TGFB1, TGFB, Latent TGF-β1
Catalog No. TMPJ-00622 Copy Product Info
Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 11 and 35-45 KDa and the accession number is F7HCV5.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $98 | 35 days | 35 days | |
| 10 µg | $160 | 35 days | 35 days | |
| 20 µg | $255 | 35 days | 35 days | |
| 50 µg | $479 | 35 days | 35 days | |
| 100 µg | $778 | 35 days | 35 days | |
| 200 µg | $1,260 | 35 days | 35 days | |
| 500 µg | $2,420 | 35 days | 35 days | |
| 1 mg | $3,630 | 35 days | 35 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 11 and 35-45 KDa and the accession number is F7HCV5. |
| Species | Cynomolgus |
| Expression System | HEK293 Cells |
| Tag | N-6xHis |
| Accession Number | F7HCV5 |
| Amino Acid | Leu30-Ser390 |
| Construction | Leu30-Ser390 (Cys33Ser) |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | Transforming growth factor β-1, Transforming growth factor beta-1 proprotein, TGFβ-1, TGFB1, TGFB, Latent TGF-β1 |
| Research Background | Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are three isoforms of TGFβ (TGFβ-1, -2 and -3). latent TGF-β1 plays a protective role against bleomycin-induced lung inflammation and fibrosis. The inhibitory effect of latent TGF-β1 on lung inflammation and fibrosis may be associated with the counter-regulatory mechanism between latent and active TGF-β 1, the negative regulatory role of Smad7 in activation of both NF-κB and TGF-β/Smad signaling pathways, and importantly, the GARP-Foxp3 regulatory mechanism in rebalancing the Treg/Th17 response. Some studies have shown that TGFB1 (Cys33Ser) mice develop multiorgan inflammation and tumors consistent with reduced TGF-b1 activity. |
| Molecular Weight | 11&35-45 KDa (reducing condition) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His) chemical structure | Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His) molecular weight
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