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Anti-CD11b Polyclonal Antibody
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Catalog No. TMAB-00330
Alias Neutrophil adherence receptor, Leukocyte adhesion receptor MO1, ITGAM, ITAM, Integrin alpha-M, CR3A, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, CD11B, CD11 b, CD11 antigen-like family member B
Anti-CD11b Polyclonal Antibody is a Rabbit antibody targeting CD11b. Anti-CD11b Polyclonal Antibody can be used in WB.
Anti-CD11b Polyclonal Antibody
Anti-CD11b Polyclonal Antibody
😃Good
Catalog No. TMAB-00330Alias Neutrophil adherence receptor, Leukocyte adhesion receptor MO1, ITGAM, ITAM, Integrin alpha-M, CR3A, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, CD11B, CD11 b, CD11 antigen-like family member B
Anti-CD11b Polyclonal Antibody is a Rabbit antibody targeting CD11b. Anti-CD11b Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $220 | 7-10 days | |
| 100 μL | $372 | 7-10 days | |
| 200 μL | $527 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-CD11b Polyclonal Antibody is a Rabbit antibody targeting CD11b. Anti-CD11b Polyclonal Antibody can be used in WB. |
| Synonyms | Neutrophil adherence receptor, Leukocyte adhesion receptor MO1, ITGAM, ITAM, Integrin alpha-M, CR3A, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, CD11B, CD11 b, CD11 antigen-like family member B |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 25 μg total protein per Lane of various lysates probed with CD11b polyclonal antibody, unconjugated (TMAB-00330) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane. |
| Tissue Specificity | Predominantly expressed in monocytes and granulocytes. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] |
| Immunogen | KLH conjugated synthetic peptide: mouse CD11b |
| Antigen Species | Mouse |
| Gene Name | ITGAM |
| Protein Name | Integrin alpha-M |
| Biology Area | Microglia marker,Alpha,Murine Lineage Negative,B Lymphocytic Lineage,NK Cell Lineage,T Lymphocytic Lineage,Monocytic Lineage,Neutrophil Lineage,Negative Markers,Glial |
| Function | Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. |
| Molecular Weight | Theoretical: 125 kDa. Actual: 165-170 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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