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Synonyms: MMP-12, Mmp12, Mmel, Mme, Matrix metalloproteinase-12, Macrophage metalloelastase

| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 µg | $183 | 35 days | 35 days | |
| 20 µg | $292 | 35 days | 35 days | |
| 50 µg | $545 | 35 days | 35 days | |
| 100 µg | $792 | 35 days | 35 days | |
| 200 µg | $1,150 | 35 days | 35 days | |
| 500 µg | $1,900 | 35 days | 35 days | |
| 1 mg | $2,970 | 35 days | 35 days |
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Matrix metalloproteinase-12(MMP12) is a secreted protein.It contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. It can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3. |
| Species | Mouse |
| Expression System | HEK293 Cells |
| Tag | C-6xHis |
| Accession Number | P34960 |
| Amino Acid | Ala29-Cys473 |
| Construction | Ala29-Cys473. The proenzyme needs to be activated by APMA for an activated form. |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) ![]() |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20 mM PB, 500 mM NaCl, 0.01%Tween 80, 1 mM EDTA, 50% Glycerol, pH6.0. |
| Synonyms | MMP-12, Mmp12, Mmel, Mme, Matrix metalloproteinase-12, Macrophage metalloelastase |
| Research Background | Matrix metalloproteinase-12(MMP12) is a secreted protein.It contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. It can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3. |
| Molecular Weight | 64 KDa (reducing condition) |
| Shipping | Proteins are shipped with blue ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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