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APRIL/TNFSF13 Protein, Mouse, Recombinant (hFc)

(Synonyms: TRDL-1, TNFSF13, TALL-2, CD256, A proliferation-inducing ligand) Copy Product Info

Synonyms: TRDL-1, TNFSF13, TALL-2, CD256, A proliferation-inducing ligand

Catalog No. TMPJ-00456 Copy Product Info
Tumor necrosis factor ligand superfamily member 13 belongs to the tumor necrosis factor family. It is also known as APRIL, TALL2, TRDL1, and CD256. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. TNFSF13 is a Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA and plays a role in the regulation of tumor cell growth. It expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages. Its expression by CD4+ T cells inhibits the production of Th2 cytokines and allergic inflammation.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$687-10 days7-10 days
10 μg$1107-10 days7-10 days
20 μg$1697-10 days7-10 days
50 μg$3107-10 days7-10 days
100 μg$4927-10 days7-10 days
200 μg$8197-10 days7-10 days
500 μg$1,5707-10 days7-10 days
1 mg$2,2307-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Tumor necrosis factor ligand superfamily member 13 belongs to the tumor necrosis factor family. It is also known as APRIL, TALL2, TRDL1, and CD256. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. TNFSF13 is a Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA and plays a role in the regulation of tumor cell growth. It expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages. Its expression by CD4+ T cells inhibits the production of Th2 cytokines and allergic inflammation.
Species
Mouse
Expression System
HEK293 Cells
TagN-hFc
Accession NumberAAG22534.1
Amino AcidAla96-Leu240
ConstructionAla96-Leu240
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 8% Sucrose, 0.05% Tween 80, pH 6.0.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsTRDL-1, TNFSF13, TALL-2, CD256, A proliferation-inducing ligand
Research Background
Chemical Properties
Molecular Weight50-60 KDa (reducing condition)
Storage & Solubility Information
StorageLyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: APRIL/TNFSF13 Protein, Mouse, Recombinant (hFc) chemical structure | APRIL/TNFSF13 Protein, Mouse, Recombinant (hFc) molecular weight