EIF3G Protein, Human, Recombinant (His & SUMO)

Name: EIF3G Protein, Human, Recombinant (His & SUMO)
Brand: TargetMol
SKU: TMPH-01310
Rating: 4.5 (1 reviews)

(Synonyms: Eukaryotic translation initiation factor 3 subunit G, Eukaryotic translation initiation factor 3 subunit 4, Eukaryotic translation initiation factor 3 RNA-binding subunit (eIF-3 RNA-binding subunit), EIF3S4, EIF3G, eIF-3-delta, eIF3 p44, eIF3 p42) Copy Product Info

Synonyms: Eukaryotic translation initiation factor 3 subunit G, Eukaryotic translation initiation factor 3 subunit 4, Eukaryotic translation initiation factor 3 RNA-binding subunit (eIF-3 RNA-binding subunit), EIF3S4, EIF3G, eIF-3-delta, eIF3 p44, eIF3 p42

Catalog No. TMPH-01310 Copy Product Info

EIF3G Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 51.5 kDa and the accession number is O75821.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$75	20 days	20 days
10 µg	$119	20 days	20 days
20 µg	$198	20 days	20 days
50 µg	$297	20 days	20 days
100 µg	$427	20 days	20 days
200 µg	$658	20 days	20 days
500 µg	$1,170	20 days	20 days
1 mg	$1,830	20 days	20 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	EIF3G Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 51.5 kDa and the accession number is O75821.
Species	Human
Expression System	E. coli
Tag	N-6xHis-SUMO
Accession Number	O75821
Amino Acid	PTGDFDSKPSWADQVEEEGEDDKCVTSELLKGIPLATGDTSPEPELLPGAPLPPPKEVINGNIKTVTEYKIDEDGKKFKIVRTFRIETRKASKAVARRKNWKKFGNSEFDPPGPNVATTTVSDDVSMTFITSKEDLNCQEEEDPMNKLKGQKIVSCRICKGDHWTTRCPYKDTLGPMQKELAEQLGLSTGEKEKLPGELEPVQATQNKTGKYVPPSLRDGASRRGESMQPNRRADDNATIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARAIAGVSGFGYDHLILNVEWAKPSTN
Construction	2-320 aa
Protein Purity	> 90% as determined by SDS-PAGE.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Tris-based buffer, 50% glycerol
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonyms	Eukaryotic translation initiation factor 3 subunit G, Eukaryotic translation initiation factor 3 subunit 4, Eukaryotic translation initiation factor 3 RNA-binding subunit (eIF-3 RNA-binding subunit), EIF3S4, EIF3G, eIF-3-delta, eIF3 p44, eIF3 p42
Research Background	RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. This subunit can bind 18S rRNA.; (Microbial infection) In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2.

Chemical Properties

Molecular Weight

51.5 kDa (predicted)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.