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Muvalaplin

🥰Excellent
Catalog No. T77695Cas No. 2565656-70-2
Alias LY3473329

Muvalaplin (LY3473329) is an orally active lipoprotein (a) [Lp(a)] reagent that inhibits Lp(a) formation by blocking apo(a)-apo B100 interactions.

Muvalaplin
Other Forms of Muvalaplin:
Muvalaplin tetrahydrochlorideT2004522565656-71-3
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Muvalaplin

🥰Excellent
Purity: 99.99%
Catalog No. T77695Alias LY3473329Cas No. 2565656-70-2
Muvalaplin (LY3473329) is an orally active lipoprotein (a) [Lp(a)] reagent that inhibits Lp(a) formation by blocking apo(a)-apo B100 interactions.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$148In StockIn Stock
5 mg$372In StockIn Stock
10 mg$546In StockIn Stock
25 mg$953In StockIn Stock
50 mg$1,180In StockIn Stock
100 mg$1,590-In Stock
200 mg$2,180-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.99%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
Muvalaplin (LY3473329) is an orally active lipoprotein (a) [Lp(a)] reagent that inhibits Lp(a) formation by blocking apo(a)-apo B100 interactions.
SynonymsLY3473329
Chemical Properties
Molecular Weight710.9
FormulaC42H54N4O6
Cas No.2565656-70-2
Smiles[C@@H](CC1=CC(CN(CC2=CC(C[C@H](C(O)=O)[C@]3(CCNC3)[H])=CC=C2)CC4=CC(C[C@H](C(O)=O)[C@]5(CCNC5)[H])=CC=C4)=CC=C1)(C(O)=O)[C@]6(CCNC6)[H]
Relative Density.1.234 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 10 mg/mL (14.07 mM), when pH is adjusted to 6. Sonication is recommended.
H2O: <0.1 mg/mL
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.4067 mL7.0333 mL14.0667 mL70.3334 mL
5 mM0.2813 mL1.4067 mL2.8133 mL14.0667 mL
10 mM0.1407 mL0.7033 mL1.4067 mL7.0333 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

MuvalaplinLY-3473329LY 3473329Lipoprotein (a)
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