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Anti-Mouse PD-1 Antibody (RMP1-14) is an IgG2a antibody inhibitor against mouse PD-1 and can block PD-1/PD-L1 signaling.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $64 | In Stock | |
5 mg | $226 | In Stock | |
10 mg | $398 | In Stock | |
25 mg | $757 | In Stock | |
50 mg | $1,090 | In Stock | |
100 mg | $1,450 | In Stock |
Description | Anti-Mouse PD-1 Antibody (RMP1-14) is an IgG2a antibody inhibitor against mouse PD-1 and can block PD-1/PD-L1 signaling. |
Targets&IC50 | PD-1/PD-L1:1.99 μg/mL, PD-1/PD-L1:4.05 μg/mL |
In vivo | METHODS: To study the antitumor activity of Anti-Mouse PD-1 Antibody, mice were subcutaneously injected with MC38 (1×10^6) or B16-hCXCR4 (5×10^5). Two weeks later, tumor-bearing mice were intraperitoneally (ip) treated with anti-PD-1 mouse antibody [RMP1-14] (5 mg/kg, twice a week for 2 weeks), Pep R (2 mg/kg, 5 days a week for 2 weeks), or both. RESULTS: Combination therapy (Pep R plus anti-PD-1) reduced the relative tumor volume (RTV) of MC38 by 2.67 times (p=0.038), while anti-PD-1 or Pep R alone did not significantly affect tumor growth. [1] |
Synonyms | Anti-mouse PD-1 (CD279) |
Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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