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Anti-Mouse PD-1 Antibody (RMP1-14)

🥰Excellent
Catalog No. T78269
Alias Anti-mouse PD-1 (CD279)

Anti-Mouse PD-1 Antibody (RMP1-14) is an IgG2a antibody inhibitor against mouse PD-1 and can block PD-1/PD-L1 signaling.

Anti-Mouse PD-1 Antibody (RMP1-14)

Anti-Mouse PD-1 Antibody (RMP1-14)

🥰Excellent
Purity: 98.01%
Catalog No. T78269Alias Anti-mouse PD-1 (CD279)
Anti-Mouse PD-1 Antibody (RMP1-14) is an IgG2a antibody inhibitor against mouse PD-1 and can block PD-1/PD-L1 signaling.
Pack SizePriceAvailabilityQuantity
1 mg$64In Stock
5 mg$226In Stock
10 mg$398In Stock
25 mg$757In Stock
50 mg$1,090In Stock
100 mg$1,450In Stock
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Batch Information

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Concentration:18.27 mg/mL
Purity:98.01%
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Product Introduction

Bioactivity
Description
Anti-Mouse PD-1 Antibody (RMP1-14) is an IgG2a antibody inhibitor against mouse PD-1 and can block PD-1/PD-L1 signaling.
Targets&IC50
PD-1/PD-L1:1.99 μg/mL, PD-1/PD-L1:4.05 μg/mL
In vivo
METHODS: To study the antitumor activity of Anti-Mouse PD-1 Antibody, mice were subcutaneously injected with MC38 (1×10^6) or B16-hCXCR4 (5×10^5). Two weeks later, tumor-bearing mice were intraperitoneally (ip) treated with anti-PD-1 mouse antibody [RMP1-14] (5 mg/kg, twice a week for 2 weeks), Pep R (2 mg/kg, 5 days a week for 2 weeks), or both.
RESULTS: Combination therapy (Pep R plus anti-PD-1) reduced the relative tumor volume (RTV) of MC38 by 2.67 times (p=0.038), while anti-PD-1 or Pep R alone did not significantly affect tumor growth. [1]
SynonymsAnti-mouse PD-1 (CD279)
Chemical Properties
Storage & Solubility Information
Storagestore at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.

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