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Anti-Keratocan Polyclonal Antibody

😃Good
Catalog No. TMAB-01019

Anti-Keratocan Polyclonal Antibody is a Rabbit antibody targeting Keratocan. Anti-Keratocan Polyclonal Antibody can be used in WB.

Anti-Keratocan Polyclonal Antibody

Anti-Keratocan Polyclonal Antibody

😃Good
Catalog No. TMAB-01019
Anti-Keratocan Polyclonal Antibody is a Rabbit antibody targeting Keratocan. Anti-Keratocan Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$221 7-10 days
100 μL$374 7-10 days
200 μL$529 7-10 days
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Product Introduction

Bioactivity
Description
Anti-Keratocan Polyclonal Antibody is a Rabbit antibody targeting Keratocan. Anti-Keratocan Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Sheep)
Verified Activity
Sample:
Muscle (Mouse) Lysate at 40 μg
Primary: Anti-Keratocan (TMAB-01019) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 38 kDa
Observed band size: 38 kDa
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted > extracellular space > extracellular matrix.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundSmall leucine-rich proteoglycans (SLRPs) such as Decorin, Biglycan, Fibromod-ulin, Keratocan, Lumican and Osteoglycin mediate extracellular matrix organization and are binding partners of TGF Beta. The Decorin core protein binds to growth factors, intercellular matrix molecules such as Fibronectin and Throm-bospondin, and to the Decorin endocytosis receptor. Fibromodulin is a collagen-binding keratan sulphate proteoglycan that influences adhesion processes of connective tissue and plays a role in fibrillogenesis by regulating collagen fibril spacing and thickness. Keratocan (KTN) develops corneal transparency and maintains the stromal matrix structure. Keratocan is a secreted protein in the extracellular matrix that binds to keratan sulfate chains. Keratocan is mainly detected in the cornea, but can also be expressed in trachea, intestine, ovary, lung and skeletal muscle. Defects in the gene encoding for Keratocan can cause cornea plana 2 (CNA2), an autosomal recessive disorder where the forward convex curvature of the cornea is flattened.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Keratocan
Antigen Species
Human
Gene ID
Uniprot ID
Biology Area
ECM Proteins,Visual system,Other ECM Proteins,Keratin
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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